Results 71 to 80 of about 52,155 (246)

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Laser-induced generation of singlet oxygen and its role in the cerebrovascular physiology [PDF]

, 2017
For over 55 years, laser technology has expanded from laboratory research to widespread fields, for example telecommunication and data storage amongst others.
Bragina, O. A., Gekaluyk, A. S., Goltsov, Alexey, Rafailov, E. U., Saranceva, E. I., Semyachkina-Glushkovskaya, O. V., Sokolovski, S. G., Tuchin, V. V.   +7 more
core   +2 more sources

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Surrogate measure of gut blood flow via superior mesenteric circulation on ultrasound in adults who underwent esophagectomy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Early enteral nutrition is recommended for critically ill patients. However, feeding an ischemic gastrointestinal tract with enteral nutrition may lead to gut necrosis. Although gut tolerance of enteral nutrition is assessed by various symptoms, none of them provide conclusive evidence of gut ischemia. We investigated the blood flow
Tomonori Narita, Kazuhiko Fukatsu, Reo Inoue, Satoshi Murakoshi, Midori Noguchi, Nana Matsumoto, Shoh Yajima, Koichi Yagi, Yoshifumi Baba   +8 more
wiley   +1 more source

Quality of life and healthcare resource utilization among adult patients with short bowel syndrome: A mixed‐methods study leveraging an integrated database

Nutrition in Clinical Practice, EarlyView.
Abstract Background Short bowel syndrome (SBS) is a chronic condition requiring parenteral nutrition (PN) support and multidisciplinary management. However, disparities in access to care and standardized treatment pathways, in addition to economic burden, remain considerable for patients.
Deborah Kuk, Brian Po‐Han Chen, Megan Gower, Michelle Kirby, Brian Terreri, Josh Feldman, Maggie McCue, Manpreet S. Mundi   +7 more
wiley   +1 more source

Laparoscopic Versus Open Approach for Strangulated Small Bowel Obstruction: A Propensity Score–Matched Analysis

World Journal of Surgery, EarlyView.
Laparoscopic surgery has gradually gained acceptance for abdominal surgical emergencies; however, limited reports exist on laparoscopic surgery for strangulated small bowel obstruction (SSBO). We aimed to demonstrate the efficacy and feasibility of laparoscopic surgery for SSBO.
Toshimichi Kobayashi, Ryota Suda, Hiroki Yamaguchi, Shoma Iida, Kanami Iwama, Takumi Seichi, Yoshihiro Nagae, Hiroyuki Higuchi, Akitoshi Ando, Itsuki Koganezawa, Masashi Nakagawa, Kei Yokozuka, Shigeto Ochiai, Takahiro Gunji, Toru Sano, Satoshi Tabuchi, Naokazu Chiba, Shigeyuki Kawachi   +17 more
wiley   +1 more source

Evaluation of Pulmonary Reperfusion Injury in Rats Undergoing Mesenteric Ischemia and Reperfusion and Protective Effect of Postconditioning on this Process

Brazilian Journal of Cardiovascular Surgery, 2015
INTRODUCTION: Some publications have demonstrated the presence of lung reperfusion injury in mesenteric ischemia and reperfusion (I/R), but under to diverse methods.
Carlos Henrique Marques dos Santos, Ricardo Dutra Aydos, Ed Nogueira Neto, Luciana Nakao Odashiro Miiji, Pedro Carvalho Cassino, Isadora Ishaq Alves, Nádia Meneguesso Calheiros, Milena Garcia   +7 more
doaj   +1 more source

Mesenteriális ischaemia-reperfúzió pulmonális távolhatását befolyásoló mechanizmusok vizsgálata = Studies on mechanisms in the pulmonary remote effect of mesenteric ischaemia-reperfusion [PDF]

, 2007
Programunk fő célja a mesenteriális ischemia-reperfúzió pulmonális távolhatásában szerepet játszó pathomechanizmusokat jellemezni a tüdő (légút és parenchyma) mechanikai tulajdonságainak, valamint gyulladásos markereknek a vizsgálatával.
Adamicza, Ágnes, Asztalos, Tibor, Hantos, Zoltán, Peták, Ferenc   +3 more
core  

The Role of Platelet Factor 4 in Local and Remote Tissue Damage in a Mouse Model of Mesenteric Ischemia/Reperfusion Injury [PDF]

, 2012
The robust inflammatory response that occurs during ischemia reperfusion (IR) injury recruits factors from both the innate and adaptive immune systems.
Ioannou, Antonis, Kannan, Lakshmi, Kowalska, M. Anna, Lapchak, Peter H., Lieberman, Linda Adelle, Lucca, Jurandir J. Dalle, Rani, Poonam, Tsokos, George C., Yoshiya, Kazuhisa   +8 more
core   +3 more sources