Results 81 to 90 of about 52,155 (246)

Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support

Artificial Organs, EarlyView.
Levels of IL‐8 and IL‐6 and their dynamics are reliable early predictors of ECLS weaning failure. ABSTRACT Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success are still not available.
Kostiantyn Kozakov, Alois Philipp, Maik Foltan, Anton Heller, Dzmitry Turtsevich, Christian Schach, Peter‐Paul Ellmauer, Walter Petermichl, Bernhard Flörchinger, Christof Schmid, Simon Schopka, Zdenek Provaznik   +11 more
wiley   +1 more source

The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]

, 2008
The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek, Igor Buchwalow, Joachim Neumann, Sona Cacanyiova, Vera Samoilova, Werner Boecker   +5 more
core   +1 more source

The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]

, 1990
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B, Cai, X, Cramer, DV, Hoffman, AL, Makowka, L, Pascualone, A, Starzl, TE, Todo, S   +7 more
core   +1 more source

Diabetes Mellitus is a Risk Factor for Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt

Alimentary Pharmacology &Therapeutics, EarlyView.
Diabetes mellitus independently increases the risk of hepatic encephalopathy following TIPS placement in patients with cirrhosis. These findings emphasize the need for careful risk assessment in patients with cirrhosis and portal hypertension complications undergoing TIPS.
Michelle Spaan, Ellen Werner, Willemijn Dijkstra, Nicole E. Erler, Diederik Bijdevaate, Sarwa Darwish Murad, Milan J. Sonneveld, Caroline M. den Hoed, Anne van Eldere, Dave S. Sprengers, Willem‐Pieter Brouwer, Robert J. de Knegt, Harry L. A. Janssen, Kay Pieterman, Sandra Coenen, Raoel Maan, Adriaan J. van der Meer   +16 more
wiley   +1 more source

Transplantation of the small intestine: the pathologist's perspective. [PDF]

, 1990
Small-bowel transplantation is now ready for clinical trials. The surgical techniques and methods for immunosuppression and monitoring bowel status have been developed in animal models over the past 30 years.
Banner, B, Cai, X, Hoffman, A, Sheahan, DG, Starzl, TE   +4 more
core  

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Acute mesenteric ischemia diagnosed via computed tomography in a dog following vehicular blunt force trauma: a Case Report

Frontiers in Veterinary Science
Acute mesenteric ischemia (AMI) refers to a group of vascular disorders that disrupt intestinal blood flow, resulting in intestinal ischemia and necrosis if left untreated. In both humans and dogs, this condition appears to be rare but deadly.
Johnny Altwal, Liz Guieu, Margaret Cook, Jessie Warhoe, Christopher Ray, Kelly Hall   +5 more
doaj   +1 more source

A new liver perfusion and preservation system for transplantation Research in large animals [PDF]

, 1990
A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris, Belzer F O, Denmark S W, Greenway C V, Guy Lebeau, Hoffmann R M, Jamieson N V, Katsuhiko Yanaga, Leonard Makowka, Mitsuo Shimada, Moore F D, Ruey Rong Hwang, Saburo Kakizoe, Starzl T E, Starzl T E, Starzl T E, Thomas E. Starzl, Williams J W   +17 more
core   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source