Results 91 to 100 of about 4,116,678 (363)

Boundary-Conforming Finite Element Methods for Twin-Screw Extruders using Spline-Based Parameterization Techniques

open access: yes, 2019
This paper presents a novel spline-based meshing technique that allows for usage of boundary-conforming meshes for unsteady flow and temperature simulations in co-rotating twin-screw extruders.
Elgeti, Stefanie   +3 more
core   +1 more source

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone   +19 more
wiley   +1 more source

Delaunay Meshing of Piecewise Smooth Complexes without Expensive Predicates

open access: yesAlgorithms, 2009
Recently a Delaunay refinement algorithm has been proposed that can mesh piecewise smooth complexes which include polyhedra, smooth and piecewise smooth surfaces, and non-manifolds.
Tamal K. Dey, Joshua A. Levine
doaj   +1 more source

Comparison of physics-based deformable registration methods for image-guided neurosurgery

open access: yesFrontiers in Digital Health, 2023
This paper compares three finite element-based methods used in a physics-based non-rigid registration approach and reports on the progress made over the last 15 years.
Nikos Chrisochoides   +14 more
doaj   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach   +11 more
wiley   +1 more source

Transonic Airfoil Flow Simulation. Part I: Mesh Generation and Inviscid Method [PDF]

open access: yesINCAS Bulletin, 2010
A calculation method for the subsonic and transonic viscous flow over airfoil using thedisplacement surface concept is described. Part I presents a mesh generation method forcomputational grid and a finite volume method for the time-dependent Euler ...
Vladimir CARDOS   +3 more
doaj   +1 more source

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad   +8 more
wiley   +1 more source

Aerodynamic Layout Designs Using of Microflaps for Flow Control of a Supersonic Finned Projectile

open access: yesXibei Gongye Daxue Xuebao, 2019
In this paper, the flow control system consists of some small microflaps located between the rear fins of the projectile. These microflaps can alter the flow field in the finned region of the projectile resulting in asymmetric pressure distribution and ...

doaj   +1 more source

Constrained CVT meshes and a comparison of triangular mesh generators

open access: yesComputational Geometry, 2009
AbstractMesh generation in regions in Euclidean space is a central task in computational science, and especially for commonly used numerical methods for the solution of partial differential equations, e.g., finite element and finite volume methods. We focus on the uniform Delaunay triangulation of planar regions and, in particular, on how one selects ...
Nguyen, Hoa   +4 more
openaire   +3 more sources

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri   +7 more
wiley   +1 more source

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