Results 81 to 90 of about 4,091,598 (363)
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Delaunay Meshing of Piecewise Smooth Complexes without Expensive Predicates
Recently a Delaunay refinement algorithm has been proposed that can mesh piecewise smooth complexes which include polyhedra, smooth and piecewise smooth surfaces, and non-manifolds.
Tamal K. Dey, Joshua A. Levine
doaj +1 more source
Polygonal finite element-based content-aware image warping
Mesh-based image warping techniques typically represent image deformation using linear functions on triangular meshes or bilinear functions on rectangular meshes. This enables simple and efficient implementation, but in turn, restricts the representation
Juan Cao+3 more
doaj +1 more source
Designing Parallel Adaptive Laplacian Smoothing for Improving Tetrahedral Mesh Quality on the GPU
Mesh quality is a critical issue in numerical computing because it directly impacts both computational efficiency and accuracy. Tetrahedral meshes are widely used in various engineering and science applications.
Ning Xi, Yingjie Sun, Lei Xiao, Gang Mei
doaj +1 more source
Generation of Polyhedral Delaunay Meshes
AbstractA polyhedral mesh fulfills the Delaunay condition if the vertices of each polyhedron are co-spherical and each polyhedron circum- sphere is point-free. If Delaunay tessellations are used together with the finite volume method, it is not necessary to partition each polyhedron into tetrahedra; co-spherical elements can be used as final elements ...
David Contreras, Nancy Hitschfeld-Kahler
openaire +2 more sources
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef+10 more
wiley +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Aerodynamic Layout Designs Using of Microflaps for Flow Control of a Supersonic Finned Projectile
In this paper, the flow control system consists of some small microflaps located between the rear fins of the projectile. These microflaps can alter the flow field in the finned region of the projectile resulting in asymmetric pressure distribution and ...
doaj +1 more source
Comparison of physics-based deformable registration methods for image-guided neurosurgery
This paper compares three finite element-based methods used in a physics-based non-rigid registration approach and reports on the progress made over the last 15 years.
Nikos Chrisochoides+14 more
doaj +1 more source