Results 31 to 40 of about 9,796 (261)
Kinematic Characteristic Analysis of Hypoid Gear based on Two Kinds of Eigenfunction
Jixie chuandong, 2021 Based on the classical space meshing theory， two kinds of basic eigenfunctions and eigenvectors of conjugate surfaces are defined. The function of the two kinds of eigenfunctions in the analysis of the meshing characteristics of conjugate surfaces is ...
Bingyang Wei +3 more
doaj
Geometry generation principle and meshing properties of a new gear drive
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018 The generation principle of composite cycloid is proposed for the tooth profile of external drive. Firstly, a two-link mechanism is developed as the equivalent mechanism to describe the geometric principle of cycloid by introducing the motion ...
Zhenhua HAN +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A Generalized Dynamic Model and Coupling Meshing Force Analysis for Planetary Gear Set Transmissions
Applied Sciences, 2022 The dynamics analysis of a planetary gear set transmissions requires the creation of completely different models for different gears, which is very tedious. In this paper, a generalized dynamics modeling process is proposed for a three planetary gear set
Haiwei Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Dynamic analysis of double-helical gear system considering effect of oil film among meshing teeth
Advances in Mechanical Engineering, 2020 The oil film among meshing teeth is just like a spring-damping element, and it can dominate the friction and meshing characteristics of the gear pair and influence its dynamic performances further.
Minghu Yin +4 more
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Clinical characteristics of patients with inguinal hernia mesh migration into the bladder
IJU Case Reports, 2022 IntroductionWe report two cases of mesh migration into the bladder after inguinal hernia surgery.Case presentationIn the first case, a 48‐year‐old woman who underwent right internal inguinal hernia repair, 18 months prior, presented with pollakiuria and microscopic hematuria that was resistant to antibiotics.
Takahiro Akimoto +5 more
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source