Results 51 to 60 of about 9,298 (261)

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Study on Meshing Efficiency of Non-circular Gear based on Elastohydrodynamic Lubrication

open access: yesJixie chuandong, 2021
Based on the analysis of the meshing characteristics of non-circular gear and the law of equal engagement angle of tooth profile, considering the influence of relative speed, friction coefficient, oil film thickness, and other key factors on the loss of ...
Wanshan Liu   +3 more
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Dynamic Analysis of High-Speed Helical Gear Transmission in Pure Electric Vehicle Gearbox

open access: yesShock and Vibration, 2020
This study is to systematically analyze the influences of time-varying meshing stiffness (TVMS) and meshing impact on the dynamic characteristics of high-speed gear transmission in the two-stage pure electric vehicle (PEV) gearbox, as well as the effect ...
Yanchao Zhang, Jinfu Du, Jin Mao, Min Xu
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi   +7 more
wiley   +1 more source

Meshing Behavior and Vibration Response of a Gear Pair Involving Eccentricity Errors

open access: yesJixie chuandong, 2022
To explore the influence of eccentricity errors on the dynamic characteristics of gear transmissions,a six-degree-of-freedom bending-torsional coupling vibration model of a spur gear pair with eccentricity error excitations is established by using the ...
Yuanyuan Yi   +4 more
doaj  

Simulation Analysis of Meshing Characteristic for Cycloid Meshing Drive of RV Reducer

open access: yesJixie chuandong, 2017
The cycloid pin wheel drive is essential to RV reducer. It is the basic point to determine the contact stiffness of cycloid and pin wheel. The equivalent contact stiffness is calculated based on Hertz contact theory. The parameters to solve the contact stiffness is checked and the stiffness model with teeth number in meshing simultaneously as a ...
Han Ju, Wang Xiaohu, Liang Liming
openaire   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

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