Results 121 to 130 of about 23,412 (303)
Distinct medial temporal volumetric signatures in extra‐medial temporal lobe lesional epilepsy
Epilepsia Open, EarlyView.Abstract Objective To quantify amygdala and hippocampal volumetric asymmetries in patients with drug‐resistant epilepsy (DRE) and extra‐medial temporal lesions (EMTLs) and to assess the prevalence of structural alterations relative to drug‐resistant temporal lobe epilepsy (TLE), extratemporal lobe epilepsy (ETLE), and healthy individuals.
Yonatan Serlin +7 more
wiley +1 more source
Histological classification of mesial temporal sclerosis
Неврология, нейропсихиатрия, психосоматика, 2016 Mesial temporal sclerosis (MTS) is the most common histopathology occurring in patients with drug-resistant temporal lobe epilepsy. Over the past decades, there have been various attempts to classify the variants of hippocampal neuronal cell loss in ...
D. V. Dmitrenko +6 more
doaj +1 more source
Laser ablation for mesial temporal lobe epilepsy: Surgical and cognitive outcomes with and without mesial temporal sclerosis [PDF]
, 2018 Cristian Donos +10 more
openalex +1 more source
The Insula and Its Epilepsies [PDF]
, 2019 Insular seizures are great mimickers of seizures originating elsewhere in the brain. The insula is a highly connected brain structure. Seizures may only become clinically evident after ictal activity propagates out of the insula with semiology that ...
Gonzalez-Martinez, Jorge +8 more
core +1 more source
Epilepsia Open, EarlyView.Abstract Accurate seizure documentation is essential in guiding treatment decisions in epilepsy but still heavily relies on highly subjective and sometimes unreliable patient reports. We report a case of medically refractory mesial temporal lobe epilepsy where subcutaneous EEG revealed persistence of seizures following add‐on antiseizure medication ...
Tamara Lisy +7 more
wiley +1 more source
SCN1A and Susceptibility to MTL Epilepsy, Hippocampal Sclerosis and Febrile Seizures
Pediatric Neurology Briefs, 2013 Investigators at the Department of Clinical and Experimental Epilepsy, Institute of Neurology, Queen Square, London, and other centers in the UK and Europe conducted a genome-wide association study in 1018 people with mesial temporal lobe epilepsy (MTLE)
J Gordon Millichap
doaj +1 more source
Abstract Seizures commonly arise from the mesial temporal lobe, and “scarring” of the hippocampus, hippocampal sclerosis, is the commonest cause of drug-resistant epilepsy. Hippocampal sclerosis stems from genetic and environmental factors, including traumatic brain injury, prolonged seizures, or inflammation. The hippocampus is not only
Nayak CS, Bandyopadhyay S.
europepmc +2 more sources
Clock gene dysregulation in epilepsy: A systematic review
Epilepsia Open, EarlyView.Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos +3 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (
Mohammad F. Khazali +14 more
wiley +1 more source
Magnetic resonance fingerprinting of temporal lobe white matter in mesial temporal lobe epilepsy
Annals of Clinical and Translational Neurology, 2019 Objective Mesial temporal lobe epilepsy (MTLE) is a network disorder. We aimed to quantify the white matter alterations in the temporal lobe of MTLE patients with hippocampal sclerosis (MTLE‐HS) by using magnetic resonance fingerprinting (MRF), a novel ...
Kang Wang +8 more
doaj +1 more source