Results 51 to 60 of about 206,413 (341)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Separating Mesoscale and Submesoscale Flows from Clustered Drifter Trajectories

Fluids, 2020
Drifters deployed in close proximity collectively provide a unique observational data set with which to separate mesoscale and submesoscale flows. In this paper we provide a principled approach for doing so by fitting observed velocities to a local ...
Sarah Oscroft, Adam M. Sykulski, Jeffrey J. Early   +2 more
doaj   +1 more source

Waveform Relaxation for the Computational Homogenization of Multiscale Magnetoquasistatic Problems

, 2016
This paper proposes the application of the waveform relaxation method to the homogenization of multiscale magnetoquasistatic problems. In the monolithic heterogeneous multiscale method, the nonlinear macroscale problem is solved using the Newton--Raphson
Geuzaine, Christophe, Niyonzima, Innocent, Schöps, Sebastian   +2 more
core   +1 more source

Mesoscale characteristics [PDF]

Journal of Geophysical Research: Oceans, 2001
The spatial length, time, and propagation characteristics of the ocean mesoscale variability are examined throughout the globe. Sea surface height (SSH) variations from a combination of the Geosat Exact Repeat Mission, ERS‐1, ERS‐2, and TOPEX/Poseidon altimeter satellites are used to compute the observed covariance of the mesoscale.
G. A. Jacobs, C. N. Barron, R. C. Rhodes
openaire   +1 more source

Packaging of Macroscopic Material Payloads: Needs, Challenges, Concepts, and Future Directions

Advanced Engineering Materials, EarlyView.
This review introduces a unified framework that decomposes any macroscopic packaging system into the payload, packaging material, and packaging strategy and combines them into a conceptual packaging equation: packaging strategy = payload + packaging material.
Venkata S. R. Jampani, Manos Anyfantakis
wiley   +1 more source

Hundred‐Meter‐Scale In Situ Observations Reveal Joint Impact of Humidity and Wind on Raindrop Microphysics

Geophysical Research Letters
The mechanisms linking raindrop size distributions (DSDs) to environmental conditions remain poorly understood, limiting their practical application. We develop a unique fine‐scale vertical in situ data set to reveal the evolution of near‐surface DSDs ...
Zitong Liu, Ang Zhou, Kun Zhao, Hongyan Luo, Long Wen, Qing Lin, Yinghui Lu, Hao Huang, Shuguang Wang, Gang Chen, Zhengwei Yang, Chunsheng Zhang, Zhi Tao, Shirui Zhang   +13 more
doaj   +1 more source

Mesoscale Dynamics [PDF]

Eos, Transactions American Geophysical Union, 2008
Mesoscale meteorology is the study of atmospheric phenomena with typical spatial scales between 10 and 1000 kilometers. Examples of mesoscale phenomena include fronts, mesoconvective systems, thunderstorms, gap winds, downslope windstorms, and land‐sea breezes.
openaire   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source

Overview of the identification of traffic accident-prone locations driven by big data

Digital Transportation and Safety, 2023
Effective identification of traffic accident-prone points can reduce accident risks and eliminate safety hazards. This paper first systematically compares the research in Chinese and foreign literature, and proposes three types of identification ...
Chunjiao Dong, Naixin Chang
doaj   +1 more source

On the potential use of radar-derived information in operational numerical weather prediction [PDF]

, 1986
Estimates of requirements likely to be levied on a new observing system for mesoscale meteonology are given. Potential observing systems for mesoscale numerical weather prediction are discussed.
Mcpherson, R. D.
core   +1 more source