Results 121 to 130 of about 100,425 (314)
Diffuse fibrous mesothelioma of the pericardium. Report of a case and review of the literature [PDF]
Clyde J. Dawe+2 more
openalex +1 more source
Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity. [PDF]
The majority of chimeric antigen receptor (CAR) T-cell research has focused on attacking cancer cells. Here, we show that targeting the tumor-promoting, nontransformed stromal cells using CAR T cells may offer several advantages.
Albelda, Steven M.+13 more
core +2 more sources
Cancer‐Type‐Specific DNA Methylation Is a Source of Vulnerability in Liver Cancer Cells
We profiled genome‐wide DNA methylation in 1165 human cancer cell lines representing 25 cancer types and identified 73 genes as potential liver cancer‐specific methylation‐silenced genes. We selected ASNS, BCAT2, FXYD5, and NQO1 genes for further experimental analysis and demonstrated that aberrant methylation of BCAT2 contributes to the vulnerability ...
Karen Minowa+3 more
wiley +1 more source
Prolonged survival in diffuse pleural mesothelioma treated with AU198 [PDF]
Ralph M. Richart, Charles D. Sherman
openalex +1 more source
A humanized cancer‐specific anti‐podoplanin monoclonal antibody humPMab‐117 exerts antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against human tumor cells. In the xenograft tumor models, humPMab‐117 demonstrated strong antitumor efficacy.
Tomohiro Tanaka+5 more
wiley +1 more source
Diffuse Mesothelioma of the Pleura and Asbestos [PDF]
P. C. Elmes, W. McCaughey, O. L. Wade
openalex +1 more source
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou+18 more
wiley +1 more source
Myeloid Cell Mobilization and Recruitment by Human Mesothelioma in NSG-SGM3 Mice
Malignant pleural mesothelioma is a neoplasm that is often detected late due to nonspecific symptoms. This study utilized NSG-SGM3 mice to examine interactions between a human-derived mesothelioma reporter cell line (MZT-Luc2-mCherry) and the host’s ...
Vadim V. Shindyapin+11 more
doaj +1 more source
Multiscale Parallel Simulation of Malignant Pleural Mesothelioma via Adaptive Domain Partitioning -- an Efficiency Analysis Study [PDF]
A novel parallel efficiency analysis on a framework for simulating the growth of Malignant Pleural Mesothelioma (MPM) tumours is presented. Proliferation of MPM tumours in the pleural space is simulated using a Cellular Potts Model (CPM) coupled with partial differential equations (PDEs).
arxiv