Results 21 to 30 of about 136,561 (344)
Molecular Cancer Therapeutics, 2021 Mutations in the neurofibromatosis type 2 (NF2) gene that limit or abrogate expression of functional Merlin are common in malignant mesothelioma. Merlin activates the Hippo pathway to suppress nuclear translocation of YAP and TAZ, the major effectors of ...
T. Tang +8 more
semanticscholar +1 more source
Must countries shoulder the burden of mesothelioma to ban asbestos? A global assessment
BMJ Global Health, 2022 Introduction Mesothelioma is a key asbestos-related disease (ARD) but can be difficult to diagnose. Countries presumably ban asbestos to reduce future ARD burdens, but it is unknown if countries ban asbestos as a consequence of ARD burdens.
Seong-Kyu Kang +10 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2008 Malignant mesothelioma is a fatal asbestos-associated malignancy originating from the lining cells (mesothelium) of the pleural and peritoneal cavities, as well as the pericardium and the tunica vaginalis. The exact prevalence is unknown but it is estimated that mesotheliomas represent less than 1% of all cancers.
Alastair J Moore +2 more
openaire +4 more sources
Assessment of Global Trends in the Diagnosis of Mesothelioma From 1990 to 2017
JAMA Network Open, 2021 Key Points Question What are the temporal trends and epidemiological distribution of mesothelioma, and have cases of mesothelioma increased worldwide since 1990?
Zhen Zhai +19 more
semanticscholar +1 more source
Estimated future incidence of malignant mesothelioma in South Korea: Projection from 2014 to 2033. [PDF]
PLoS ONE, 2017 Malignant mesothelioma is a malignant tumor on the pleura or the peritoneum caused mostly by asbestos. Although asbestos is not currently used in South Korea, the incidence of mesothelioma is increasing due to its long latent period. This study predicted
Kyeong Min Kwak +3 more
doaj +1 more source
Asbestos Consumption and Malignant Mesothelioma Mortality Trends in the Major User Countries
Annals of Global Health, 2023 Background: The causal association between mesothelioma and asbestos exposure is conclusive, and many studies have proved that the trend in asbestos use is a strong predictor of the pattern in mesothelioma cases with an adequate latency time (generally ...
Claudio Gariazzo +2 more
doaj +1 more source
Update on biology and management of mesothelioma
European Respiratory Review, 2021 Malignant pleural mesothelioma is an aggressive, incurable cancer that is usually caused by asbestos exposure several decades before symptoms arise. Despite widespread prohibition of asbestos production and supply, its incidence continues to increase. It
R. Asciak, V. George, N. Rahman
semanticscholar +1 more source
Mitochondrial ROS Induce Partial Dedifferentiation of Human Mesothelioma via Upregulation of NANOG
Antioxidants, 2020 The expression of pluripotency factors is a key regulator of tumor differentiation status and cancer stem cells. The purpose of this study was to examine the expression of pluripotency factors and differentiation status of human mesothelioma and the role
Filip Sedlic +8 more
doaj +1 more source
Understanding clinical decision-making in mesothelioma care: a mixed methods study
BMJ Open Respiratory Research, 2022 Introduction Malignant pleural mesothelioma is a rare, incurable cancer arising from previous asbestos exposure; patients have a poor prognosis, with a median survival rate of 8–14 months. Variation in mesothelioma clinical decision-making remains common
Najib Rahman +9 more
doaj +1 more source
Epidemiology and Clinical Aspects of Malignant Pleural Mesothelioma
Cancers, 2021 Simple Summary Mesothelioma is a cancer of the lining of the lungs caused by breathing in asbestos fibres. Asbestos was widely used in industry in the last century in most developed countries and is still present in many older buildings to this day ...
F. Brims
semanticscholar +1 more source