Results 31 to 40 of about 57,565 (259)

Living with mesothelioma: a systematic review of mental health and well-being impacts and interventions for patients and their informal carers

BMJ Open
Objectives Mesothelioma is an aggressive cancer predominantly affecting the lung and abdominal linings. It can have a unique impact on mental health and well-being (MHWB) due to its incurability, poor prognosis and asbestos-exposure causation.
Clare Gardiner, Bethany Taylor, Angela Mary Tod, Stephanie Ejegi-Memeh, Virginia Sherborne, Sarah Hargreaves   +5 more
doaj   +1 more source

Malignant Peritoneum Mesothelioma with Hepatic Involvement: A Single Institution Experience in 5 Patients and Review of the Literature

Gastroenterology Research and Practice, 2016
Malignant peritoneal mesothelioma with invasion of the liver is an invariably fatal disease. We aimed to clarify the characteristics of malignant peritoneal mesothelioma cases with liver involvement. The clinical presentation, computed tomography images,
Shan-shan Su, Guo-qi Zheng, Ya-gang Liu, Yue-feng Chen, Zhao-wei Song, Shu-jing Yu, Ning-ning Sun, Yu-xin Yang   +7 more
doaj   +1 more source

BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state. [PDF]

PLoS ONE, 2018
Malignant pleural mesothelioma is an aggressive cancer with poor prognosis. Here we have investigated in vitro efficacy of BAMLET and BLAGLET complexes (anti-cancer complexes consisting of oleic acid and bovine α-lactalbumin or β-lactoglobulin ...
Emma M Rath, Yuen Yee Cheng, Mark Pinese, Kadir H Sarun, Amanda L Hudson, Christopher Weir, Yiwei D Wang, Anders P Håkansson, Viive M Howell, Guo Jun Liu, Glen Reid, Robert B Knott, Anthony P Duff, W Bret Church   +13 more
doaj   +1 more source

The therapeutic potential of the novel ribonuclease ranpirnase (Onconase®) in the treatment of malignant mesothelioma

Oncology Reviews, 2011
Ribonucleases are a superfamily of RNA-cleaving enzymes that can be cytotoxic since the cleavage of RNA makes its information indecipherable. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA, thus leading to an inhibition of protein ...
Luciano Mutti, Giovanni Gaudino
doaj   +2 more sources

Communicating imaging findings in peritoneal mesothelioma: the impact of ‘PAUSE’ on surgical decision-making

Insights into Imaging, 2021
The peritoneal cavity is the second commonest site of mesothelioma after the pleural cavity. There are five histological types of peritoneal mesothelioma with variable symptomatology, clinical presentation and prognosis.
Anuradha Chandramohan, Nehal Shah, Andrew Thrower, Norman John Carr, Rohin Mittal, Faheez Mohamed, Brendan Moran   +6 more
doaj   +1 more source

Primary pericardial mesothelioma presenting as constrictive pericarditis [PDF]

Archive of Oncology, 2005
Primary pericardial mesothelioma is an extremely rare and lethal cardiac tumor. We report an autopsy case of a primary pericardial mesothelioma in a 52-year-old man.
Karadžić Radovan, Kostić-Banović Lidija, Antović Aleksandra, Čelar Marko, Katić Vuka V., Ilić Goran, Stojanović Jovan   +6 more
doaj   +1 more source

Relations between approved platinum drugs and non-coding RNAs in mesothelioma

Non-coding RNA Research, 2018
Malignant mesothelioma diseases feature an increasing risk due to their severe forms and their association with asbestos exposure. Platinum(II) complexes such as cisplatin and carboplatin are clinically approved for the therapy of mesothelioma often in ...
Bernhard Biersack
doaj   +1 more source

Aberrant expression of NPPB through YAP1 and TAZ activation in mesothelioma with Hippo pathway gene alterations

Cancer Medicine, 2023
Background Mesothelioma is a neoplastic disease associated with asbestos exposure. It is highly malignant and has a poor prognosis; thus, early detection is desirable. Recent whole‐genome analysis has revealed that mesothelioma is characterized by a high
Tatsuhiro Sato, Ken Akao, Ayuko Sato, Tohru Tsujimura, Satomi Mukai, Yoshitaka Sekido   +5 more
doaj   +1 more source

The experience of mesothelioma in Northern England [PDF]

, 2007
Mesothelioma is a potentially preventable fatal disease causing almost 2000 deaths/year in the UK, increasing in incidence, and lacking effective treatments.
Clayson, Helen
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source