Results 21 to 30 of about 42,556 (220)

Malignant Mesothelioma [PDF]

open access: yesCancers, 2021
Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos [...]
Daniel L. Pouliquen, Joanna Kopecka
openaire   +3 more sources

Certified causes of death in patients with mesothelioma in South East England

open access: yesBMC Cancer, 2009
Background Mesothelioma is a highly fatal cancer that is caused by exposure to asbestos fibres. In many populations, the occurrence of mesothelioma is monitored with the use of mortality data from death certification. We examine certified causes of death
Peto Julian   +4 more
doaj   +1 more source

Living with mesothelioma: a systematic review of mental health and well-being impacts and interventions for patients and their informal carers

open access: yesBMJ Open
Objectives Mesothelioma is an aggressive cancer predominantly affecting the lung and abdominal linings. It can have a unique impact on mental health and well-being (MHWB) due to its incurability, poor prognosis and asbestos-exposure causation.
Clare Gardiner   +5 more
doaj   +1 more source

Changing Pattern in Malignant Mesothelioma Survival

open access: yesTranslational Oncology, 2015
Survival for mesothelioma has been shown to be poor, with marginal improvement over time. Recent advances in the understanding of pathophysiology and treatment of mesothelioma may impact therapy to improve survival that may not be evident from available ...
Jennifer Faig   +5 more
doaj   +1 more source

The therapeutic potential of the novel ribonuclease ranpirnase (Onconase®) in the treatment of malignant mesothelioma

open access: yesOncology Reviews, 2011
Ribonucleases are a superfamily of RNA-cleaving enzymes that can be cytotoxic since the cleavage of RNA makes its information indecipherable. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA, thus leading to an inhibition of protein ...
Luciano Mutti, Giovanni Gaudino
doaj   +2 more sources

Malignant Peritoneum Mesothelioma with Hepatic Involvement: A Single Institution Experience in 5 Patients and Review of the Literature

open access: yesGastroenterology Research and Practice, 2016
Malignant peritoneal mesothelioma with invasion of the liver is an invariably fatal disease. We aimed to clarify the characteristics of malignant peritoneal mesothelioma cases with liver involvement. The clinical presentation, computed tomography images,
Shan-shan Su   +7 more
doaj   +1 more source

BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state. [PDF]

open access: yesPLoS ONE, 2018
Malignant pleural mesothelioma is an aggressive cancer with poor prognosis. Here we have investigated in vitro efficacy of BAMLET and BLAGLET complexes (anti-cancer complexes consisting of oleic acid and bovine α-lactalbumin or β-lactoglobulin ...
Emma M Rath   +13 more
doaj   +1 more source

Communicating imaging findings in peritoneal mesothelioma: the impact of ‘PAUSE’ on surgical decision-making

open access: yesInsights into Imaging, 2021
The peritoneal cavity is the second commonest site of mesothelioma after the pleural cavity. There are five histological types of peritoneal mesothelioma with variable symptomatology, clinical presentation and prognosis.
Anuradha Chandramohan   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Relations between approved platinum drugs and non-coding RNAs in mesothelioma

open access: yesNon-coding RNA Research, 2018
Malignant mesothelioma diseases feature an increasing risk due to their severe forms and their association with asbestos exposure. Platinum(II) complexes such as cisplatin and carboplatin are clinically approved for the therapy of mesothelioma often in ...
Bernhard Biersack
doaj   +1 more source

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