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Mesothelioma arises from the surface serosal cells lining the pleural, peritoneal, and pericardial cavities. It has three variants including: epithelioid, sarcomatous/desmoplastic, and biphasic types. Mesothelioma cells, predominantly of the epithelioid type, can shed into effusions as sheets, clusters/ morulae, papillae, or single cells.
Rao, Nagarjun, Wei, Shuanzeng
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Malignant pleural mesothelioma (MPM) is a rare cancer mostly associated with asbestos exposure (reviewed in1) although very recently it has been found that germline mutations in BRCA1 associated protein-1 (BAP1) may predispose to mesothelioma development
Emanuela Felley-Bosco +3 more
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Interleukin 32 Expression in Mesothelioma [PDF]
Background Interleukin 32 (IL32) has context‐dependent roles in carcinogenesis across cancer types. In this study, we examined IL32 in mesotheliomas.
Takuya Mikamo +3 more
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The experience of mesothelioma in Northern England [PDF]
Mesothelioma is a potentially preventable fatal disease causing almost 2000 deaths/year in the UK, increasing in incidence, and lacking effective treatments.
Clayson, Helen
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Malignant mesothelioma is a disease affecting serosal surfaces derived from the mesothelium comprising the pleura, peritoneum, pericardium, and tunica vaginalis testis [...]
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Objectives Malignant mesothelioma is an aggressive malignancy of mesothelial surfaces, most commonly those of the pleura. The aim of this study was to understand, using a national questionnaire, the gendered care experiences of patients with malignant ...
Liz Darlison +4 more
doaj +1 more source
Summary: Background: Currently, there is no US Food and Drug Administration approved therapy for patients with pleural mesothelioma who have relapsed following platinum-doublet based chemotherapy. Vinorelbine has demonstrated useful clinical activity in
Dean A. Fennell +16 more
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The therapeutic implications of the genomic analysis of malignant pleural mesothelioma
Delineation of the genomic complexities of malignant pleural mesothelioma (MPM) has lagged behind other malignancies. Zhang et al. meaningfully add to our understanding of MPM, and their findings emphasize the need to combine drug development efforts ...
Marjorie G. Zauderer
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Must countries shoulder the burden of mesothelioma to ban asbestos? A global assessment
Introduction Mesothelioma is a key asbestos-related disease (ARD) but can be difficult to diagnose. Countries presumably ban asbestos to reduce future ARD burdens, but it is unknown if countries ban asbestos as a consequence of ARD burdens.
Seong-Kyu Kang +10 more
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Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos [...]
Daniel L. Pouliquen, Joanna Kopecka
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