Results 11 to 20 of about 111,076 (331)

Malignant Mesothelioma [PDF]

open access: yesCancers, 2021
Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos [...]
Daniel L. Pouliquen, Joanna Kopecka
openaire   +3 more sources

Mesothelioma [PDF]

open access: yesCancers, 2021
Malignant mesothelioma is a disease affecting serosal surfaces derived from the mesothelium comprising the pleura, peritoneum, pericardium, and tunica vaginalis testis [...]
openaire   +2 more sources

Malignant pleural mesothelioma patients’ experience by gender: findings from a cross-sectional UK-national questionnaire

open access: yesBMJ Open Respiratory Research, 2022
Objectives Malignant mesothelioma is an aggressive malignancy of mesothelial surfaces, most commonly those of the pleura. The aim of this study was to understand, using a national questionnaire, the gendered care experiences of patients with malignant ...
Liz Darlison   +4 more
doaj   +1 more source

Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial

open access: yesEClinicalMedicine, 2022
Summary: Background: Currently, there is no US Food and Drug Administration approved therapy for patients with pleural mesothelioma who have relapsed following platinum-doublet based chemotherapy. Vinorelbine has demonstrated useful clinical activity in
Dean A. Fennell   +16 more
doaj   +1 more source

Mesothelioma

open access: yesCytojournal, 2022
Mesothelioma arises from the surface serosal cells lining the pleural, peritoneal, and pericardial cavities. It has three variants including: epithelioid, sarcomatous/desmoplastic, and biphasic types. Mesothelioma cells, predominantly of the epithelioid type, can shed into effusions as sheets, clusters/ morulae, papillae, or single cells.
Rao, Nagarjun, Wei, Shuanzeng
openaire   +3 more sources

The therapeutic implications of the genomic analysis of malignant pleural mesothelioma

open access: yesNature Communications, 2021
Delineation of the genomic complexities of malignant pleural mesothelioma (MPM) has lagged behind other malignancies. Zhang et al. meaningfully add to our understanding of MPM, and their findings emphasize the need to combine drug development efforts ...
Marjorie G. Zauderer
doaj   +1 more source

Must countries shoulder the burden of mesothelioma to ban asbestos? A global assessment

open access: yesBMJ Global Health, 2022
Introduction Mesothelioma is a key asbestos-related disease (ARD) but can be difficult to diagnose. Countries presumably ban asbestos to reduce future ARD burdens, but it is unknown if countries ban asbestos as a consequence of ARD burdens.
Seong-Kyu Kang   +10 more
doaj   +1 more source

Understanding clinical decision-making in mesothelioma care: a mixed methods study

open access: yesBMJ Open Respiratory Research, 2022
Introduction Malignant pleural mesothelioma is a rare, incurable cancer arising from previous asbestos exposure; patients have a poor prognosis, with a median survival rate of 8–14 months. Variation in mesothelioma clinical decision-making remains common
Najib Rahman   +9 more
doaj   +1 more source

Mitochondrial ROS Induce Partial Dedifferentiation of Human Mesothelioma via Upregulation of NANOG

open access: yesAntioxidants, 2020
The expression of pluripotency factors is a key regulator of tumor differentiation status and cancer stem cells. The purpose of this study was to examine the expression of pluripotency factors and differentiation status of human mesothelioma and the role
Filip Sedlic   +8 more
doaj   +1 more source

Meet the researchers: an alternative method of engaging patients with research in mesothelioma

open access: yesResearch Involvement and Engagement, 2018
Plain English summary There are new ways to engage people with science and research but many patient support groups and charitable organisations still hold traditional meetings to provide updates on their activities and to report new developments in ...
Kate Hill, Mags Portman, Zsuzsanna Tabi
doaj   +1 more source

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