Matrix Metalloproteinases as Biomarkers and Treatment Targets in Mesothelioma: A Systematic Review
Biomolecules, 2021 Metalloproteinases (MMPs) have an important role in tissue remodeling and have been shown to have an effect on tumor progression, invasion, metastasis formation, and apoptosis in several tumors, including mesothelioma.
Danijela Štrbac, Vita Dolžan
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Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography [PDF]
, 2017 Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs.
Aquino +35 more
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Survival prediction in mesothelioma using a scalable lasso regression model: instructions for use and initial performance using clinical predictors [PDF]
, 2018 Introduction: Accurate prognostication is difficult in malignant pleural mesothelioma (MPM). We developed a set of robust computational models to quantify the prognostic value of routinely available clinical data, which form the basis of published MPM ...
Blyth, Kevin G. +5 more
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Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas. [PDF]
, 2016 Malignant pleural mesothelioma (MPM), a rare malignancy with a poor prognosis, is mainly caused by exposure to asbestos or other organic fibers, but the underlying genetic mechanism is not fully understood.
Fang, Li Tai +11 more
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, 2021 Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even ...
de Hingh, I., +12 more
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Pathologic diagnosis of malignant mesothelioma: chronological prospect and advent of recommendations and guidelines [PDF]
, 2015 Malignant mesothelioma is rare and difficult to diagnose. Its identification depends upon pathological investigation (cyto-histological assessment and immunohistochemistry) supported by clinical and radiological evidence.
Ascoli, Valeria
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Cells, 2021 Mesothelioma is an aggressive cancer associated with asbestos exposure. RNA-binding motif protein 8a (RBM8A) mRNA editing increases in mouse tissues upon asbestos exposure.
Asra Abukar +11 more
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An Unusual Cause of Abdominal Ascites. [PDF]
, 2018 Abdominal ascites is most commonly caused by portal hypertension from liver cirrhosis. When present, portal hypertension is associated with an elevated serum-ascites albumin gradient (SAAG) ≥1.1 g/dL. In contrast, a SAAG < 1.1 g/dL suggests malignancy,
Chak, Eric W +2 more
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Pediatric patient with peritoneal mesothelioma harboring ALK rearrangement
Current Problems in Cancer: Case Reports, 2021 Malignant mesothelioma is a rare disease that typically occurs in older patients with prolonged exposure to asbestos. The majority of mesothelioma occurs in the pleura.
Reema A Patel, MD +10 more
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Breast cancer or metastasis? An unusual case of metastatic malignant pleural mesothelioma to the breast [PDF]
, 2015 Background: Metastases to the breast from extramammary malignancies are very rare, and ruling out the diagnosis of primary breast tumor is important in order to decide on clinical management and predict prognosis.
Derme, Martina +5 more
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