Results 51 to 60 of about 136,561 (344)

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline.

Journal of Clinical Oncology, 2018
Purpose To provide evidence-based recommendations to practicing physicians and others on the management of malignant pleural mesothelioma. Methods ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary ...
H. Kindler, Nofisat Ismaila, S. Armato, R. Bueno, M. Hesdorffer, T. Jahan, C. M. Jones, M. Miettinen, H. Pass, A. Rimner, V. Rusch, D. Sterman, Anish Thomas, R. Hassan   +13 more
semanticscholar   +1 more source

SYSTEMS-2: a randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma [PDF]

, 2018
SYSTEMS-2 is a randomised study of radiotherapy dose escalation for pain control in 112 patients with malignant pleural mesothelioma (MPM). Standard palliative (20Gy/5#) or dose escalated treatment (36Gy/6#) will be delivered using advanced radiotherapy ...
Alexander, L., Ashton, M., Chalmers, A.J., Currie, S., Franks, K., Kelly, C., Laird, B., Macleod, N., Moore, K., O'Rourke, N., Stobo, J., Valentine, R.   +11 more
core   +2 more sources

An Unusual Cause of Abdominal Ascites. [PDF]

, 2018
Abdominal ascites is most commonly caused by portal hypertension from liver cirrhosis. When present, portal hypertension is associated with an elevated serum-ascites albumin gradient (SAAG) ≥1.1 g/dL. In contrast, a SAAG < 1.1 g/dL suggests malignancy,
Chak, Eric W, Olson, Kristin A, Wong, Kimberly A   +2 more
core   +2 more sources

Certified causes of death in patients with mesothelioma in South East England

BMC Cancer, 2009
Background Mesothelioma is a highly fatal cancer that is caused by exposure to asbestos fibres. In many populations, the occurrence of mesothelioma is monitored with the use of mortality data from death certification. We examine certified causes of death
Peto Julian, Nicholson Andrew G, Treasure Tom, Okello Catherine, Møller Henrik   +4 more
doaj   +1 more source

Breast cancer or metastasis? An unusual case of metastatic malignant pleural mesothelioma to the breast [PDF]

, 2015
Background: Metastases to the breast from extramammary malignancies are very rare, and ruling out the diagnosis of primary breast tumor is important in order to decide on clinical management and predict prognosis.
Derme, Martina, FRAMARINO DEI MALATESTA, Marialuisa, Iannini, Isabella, Masselli, Gabriele, Pecorella, Irene, Sammartino, Paolo   +5 more
core   +2 more sources

The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma

, 2021
Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even ...
de Hingh, I.,, Deraco, M.,, Glehen, O.,, Govaerts, K.,, Kepenekian, V.,, Kusamura, S.,, Lund University., Lurvink, R.J,, Moran, B.,, PSOGI, Syk, Ingvar,, Van der Speeten, K.,, Villeneuve, L.,   +12 more
core   +1 more source

Malignant Peritoneum Mesothelioma with Hepatic Involvement: A Single Institution Experience in 5 Patients and Review of the Literature

Gastroenterology Research and Practice, 2016
Malignant peritoneal mesothelioma with invasion of the liver is an invariably fatal disease. We aimed to clarify the characteristics of malignant peritoneal mesothelioma cases with liver involvement. The clinical presentation, computed tomography images,
Shan-shan Su, Guo-qi Zheng, Ya-gang Liu, Yue-feng Chen, Zhao-wei Song, Shu-jing Yu, Ning-ning Sun, Yu-xin Yang   +7 more
doaj   +1 more source

Changing Pattern in Malignant Mesothelioma Survival

Translational Oncology, 2015
Survival for mesothelioma has been shown to be poor, with marginal improvement over time. Recent advances in the understanding of pathophysiology and treatment of mesothelioma may impact therapy to improve survival that may not be evident from available ...
Jennifer Faig, Suzanne Howard, Edward A. Levine, Gary Casselman, Mary Hesdorffer, Jill A. Ohar   +5 more
doaj   +1 more source

Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burden of mesothelioma

Journal of Translational Medicine, 2023
Mesothelioma is a cancer typically caused by asbestos. Mechanistically, asbestos carcinogenesis has been linked to the asbestos-induced release of HMGB1 from the nucleus to the cytoplasm, where HMGB1 promotes autophagy and cell survival, and to the ...
Michele Carbone, Michael Minaai, Yasutaka Takinishi, Ian Pagano, Haining Yang   +4 more
doaj   +1 more source

Efficacy and Safety of Avelumab Treatment in Patients With Advanced Unresectable Mesothelioma: Phase 1b Results From the JAVELIN Solid Tumor Trial

JAMA Oncology, 2019
Importance Patients with malignant mesothelioma whose disease has progressed after platinum and pemetrexed treatment have limited options. Anti–programmed cell death 1 (PD-1) antibodies have antitumor activity in this disease, but little is known about ...
R. Hassan, Anish Thomas, J. Nemunaitis, M. Patel, J. Bennouna, Franklin L. Chen, J. Delord, A. Dowlati, S. T. Kochuparambil, Matthew H. Taylor, J. Powderly, U. Vaishampayan, C. Verschraegen, H. Grote, A. von Heydebreck, K. Chin, J. Gulley   +16 more
semanticscholar   +1 more source