Results 71 to 80 of about 63,312 (252)

The Economic Costs of Health Service Treatments for Asbestos-Related Mesothelioma Deaths

, 2006
This article explores the complex and neglected picture of occupational and environmental disease healthcare costs specifically relating to asbestos. Diagnosed mesothelioma cases in Scotland in one calendar year were used to investigate the subject in ...
Malcolm, C., Gorman, Thomas, Watterson, A., CARI MALCOLM, Robinson, M., Malcolm, Cari; id_orcid, Beck, M., Watterson, Andrew, Malcolm, Cari, MAVIS ROBINSON, Robinson, Mavis, Gorman, Tommy, MATTHIAS BECK, TOMMY GORMAN, Beck, Matthias, ANDREW WATTERSON, Gorman, T.   +16 more
core   +1 more source

Pleural Mesothelioma With Unusual Squamous Differentiation: A Clinicopathological Case Report With Molecular Insights From Whole‐Exome Sequencing [PDF]

Pathol Int
This case report highlights a rare histological variant of pleural mesothelioma with partially squamous differentiation in an 81‐year‐old man with occupational asbestos exposure. In addition to histological, immunohistochemical and fluorescence in situ hybridization analyses, indicating a common mesothelial origin of both tumor components, whole‐exome ...
Bodemeyer J, Mierzwa M, Seraphin J, Maroun R, Körber W, Engelke C, Bremmer F, Rosenthal T, Heißenberg T, Reuter‐Jessen K, Ströbel P, Marx A, Bohnenberger H.   +12 more
europepmc   +2 more sources

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Preclinical characterization and phase 1 clinical testing of targeting mitochondrial peroxiredoxin 3 in cancer

Nature Communications
Cancer cells counteract oxidative stress through upregulation of antioxidant networks. Peroxiredoxin 3 (PRX3), a mitochondrial antioxidant enzyme, regulates reactive oxygen species homeostasis and promotes tumor cell survival.
Victoria Gibson, Joanna Dzialo, Terri Messier, Aleksandra Bzura, Charlotte Poile, Jan Rogel, Jens C. Hahne, Aida Habibovic, Stephanie Stead, Alexis Saaman, Kevin G. Blyth, Peter W. Szlosarek, Simon Lord, Fiona Thistlethwaite, Min Zhang, Apostolos Nakas, Peter Wells-Jordan, Kudzayi Kutywayo, Kelly J. Butnor, Nicholas. H. Heintz, George N. Naumov, Maurice Dungey, Julio Herrero Colomina, Burak Aktas, Sean Dulloo, James Spicer, Dean A. Fennell, Brian Cunniff   +27 more
doaj   +1 more source

Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype. [PDF]

PLoS ONE, 2009
BACKGROUND: Malignant pleural mesothelioma is considered an almost incurable tumour with increasing incidence worldwide. It usually develops in the parietal pleura, from mesothelial lining or submesothelial cells, subsequently invading the visceral ...
Oluf Dimitri Røe, Endre Anderssen, Eli Helge, Caroline Hild Pettersen, Karina Standahl Olsen, Helmut Sandeck, Rune Haaverstad, Steinar Lundgren, Erik Larsson   +8 more
doaj   +1 more source

Characteristics of ascitic fluid and diagnosis of bacterial peritonitis in malignant ascites: An observational study

Journal of Hospital Medicine, EarlyView.
Abstract Background Bacterial peritonitis in patients with malignant ascites (BP‐MA) is an understudied, high‐mortality condition. While ascitic polymorphonuclear (PMN) cell count ≥ 250 cells/mm3 defines the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis, an ascitic fluid parameter for the diagnosis of BP‐MA has not ...
Mark M. Kelly, Nicole Johnston, Joanne Kuznicki, Stacy A. Johnson, Hannah Imlay   +4 more
wiley   +1 more source

Mesothelioma akibat inhalasi debu asbes [PDF]

, 2020
Mesothelioma adalah kanker yang berkembang mengenai lapisan paru-paru, adomen, atau jantung. Risiko mesothelioma tidak turun dari waktu kewaktu setelah paparan asbes berhenti. Sebanyak 80% mesothelioma disebabkan oleh inhalasi debu asbes.
Samara, Tjam Diana, Safitri, Paluvi, Maisarah, Syadza, Fitriyani, Meylan, Shahnaz, Puti, Sabrina, Isra   +5 more
core   +1 more source

Circulating SMRP and CA‐125 before and after pleurectomy decortication for pleural mesothelioma

Thoracic Cancer
Background Tumor recurrence remains the main barrier to survival after surgery for pleural mesothelioma (PM). Soluble mesothelin‐related protein (SMRP) and cancer antigen 125 (CA‐125) are established blood‐based biomarkers for monitoring PM.
Juuso Paajanen, Ahmed Sadek, William G. Richards, Yue Xie, Emanuele Mazzola, Kristina Sidopoulos, John Kuckelman, Ritu R. Gill, Raphael Bueno   +8 more
doaj   +1 more source

Pleural Mesothelioma Presenting as Periumbilical Metastasis: The First Clinical Documentation

Case Reports in Oncological Medicine, 2013
Introduction. Pleural mesothelioma with metastasis to the subcutaneous tissue of the abdominal wall at first diagnosis and without penetration into the peritoneum is an extremely rare clinical presentation. Methods.
R. F. Falkenstern-Ge, M. Kimmich, S. Bode-Erdmann, G. Friedel, G. Ott, M. Kohlhäufl   +5 more
doaj   +1 more source

Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burden of mesothelioma

Journal of Translational Medicine, 2023
Mesothelioma is a cancer typically caused by asbestos. Mechanistically, asbestos carcinogenesis has been linked to the asbestos-induced release of HMGB1 from the nucleus to the cytoplasm, where HMGB1 promotes autophagy and cell survival, and to the ...
Michele Carbone, Michael Minaai, Yasutaka Takinishi, Ian Pagano, Haining Yang   +4 more
doaj   +1 more source