Results 91 to 100 of about 42,556 (220)
Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang +4 more
wiley +1 more source
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Single‐cell RNA sequencing (scRNA‐seq) has transformed the study of cellular heterogeneity by making it possible to classify individual cells and their functional states. However, the analysis remains difficult because high dropout rates lead to sparse and noisy expression data.
Shahriar Rahman Niloy +5 more
wiley +1 more source
What's Your Diagnosis? Large Mediastinal Mass in a Dog
Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz +7 more
wiley +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Traffic, Volume 27, Issue 3, September 2026.Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Frontiers in OncologyThe malignant mesothelioma mainly develops in the pleura and peritoneum, while primary ovarian mesothelioma is very rare. Here, we report the first case of primary ovarian mesothelioma (clear cell variant) with VHL mutations in the world based on the ...
Ye Yao, Hao Yan, Jing Xiong, Yaqi Duan
doaj +1 more source
Cancer Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background Human epidermal growth factor receptor 2 (HER2), mismatch repair (MMR) proteins, claudin‐18 isoform 2 (CLDN18.2), and the programmed cell death ligand‐1 combined positive score (PD‐L1 CPS) are predictive biomarkers for the efficacy of combination chemotherapy in patients with locally advanced unresectable or metastatic gastric or ...
Daichi Takagi +10 more
wiley +1 more source
TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang +8 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims Solid tumors emerge from uncontrolled cell division and interactions with neighboring cells that influence their growth and resistance to therapy. Anti‐cancer drugs are developed to disrupt these processes, but they often damage healthy cells, making treatment difficult to manage safely and effectively. As the global cancer
Mohsin Kamran +3 more
wiley +1 more source