Results 81 to 90 of about 57,565 (259)

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

International Journal of Cancer, EarlyView.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel, Theresa Lowinus, Patrick Metzger, Rebecca Czurda, Vincent Schipperges, Ulrike Paul, Alessandra Rünger, Julian Kött, Isabel Heidrich, Saskia Lehr, Julia Kühn, Heiko Becker, Cornelius Miething, Martin Werner, Silke Laßmann, Justus Duyster, Tilman Brummer, Ronald Simon, Winfried Alsdorf, Maximilian Christopeit, Carsten Bokemeyer, Kilian Eyerich, Stefan W. Schneider, David Rafei, Melanie Börries, Frank Meiss, Christoffer Gebhardt   +26 more
wiley   +1 more source

Intercellular Communication in Malignant Pleural Mesothelioma: Properties of Tunneling Nanotubes

Frontiers in Physiology, 2014
Malignant pleural mesothelioma is a particularly aggressive and locally invasive malignancy with a poor prognosis despite advances in understanding of cancer cell biology and development of new therapies.
Justin William Ady, Snider eDesir, Snider eDesir, Venugopal eThayanithy, Rachel Isaksson Vogel, André L. Moreira, Robert John Downey, Yuman eFong, Katia eManova-Todorova, Malcolm A. S. Moore, Emil eLou   +10 more
doaj   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, EarlyView.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

Integrative eQTL and Mendelian randomization analysis reveals key genetic markers in mesothelioma

Respiratory Research
Background Mesothelioma is a rare cancer that originates from the pleura and peritoneum, with its incidence increasing due to asbestos exposure. Patients are frequently diagnosed at advanced stages, resulting in poor survival rates.
Jinsong Li, Xingmeng Wang, Yaru Lin, Zhengliang Li, Wei Xiong   +4 more
doaj   +1 more source

Comments on the Causation of Malignant Mesothelioma: Rebutting the False Concept That Recent Exposures to Asbestos Do Not Contribute to Causation of Mesothelioma

Annals of Global Health, 2016
Background: European asbestos manufacturers and their expert witnesses have advanced the claim that recent exposures to asbestos are not of significance in the causation of malignant mesothelioma.
Phillip J. Landrigan, Collegium Ramazzini   +1 more
doaj   +1 more source

Mesothelioma akibat inhalasi debu asbes

, 2020
Mesothelioma adalah kanker yang berkembang mengenai lapisan paru-paru, adomen, atau jantung. Risiko mesothelioma tidak turun dari waktu kewaktu setelah paparan asbes berhenti. Sebanyak 80% mesothelioma disebabkan oleh inhalasi debu asbes.
Samara, Tjam Diana, Safitri, Paluvi, Maisarah, Syadza, Fitriyani, Meylan, Shahnaz, Puti, Sabrina, Isra   +5 more
core   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Pleuropericardial mesotheliomas: A report of two unusual cases

Asian Journal of Oncology, 2018
Mesothelioma is an aggressive malignant tumor of the mesothelium. The majority of mesotheliomas arise from the pleura. However, less commonly mesothelioma can arise in other locations such as peritoneal, pericardium, or tunica vaginalis testis. We report
Harsha Vardhana Kuruba Ramanjaneyulu, Anu Kapoor, Chinmayee Biswal, Phani Chakravrty Mutnuru   +3 more
doaj   +1 more source

Anti-Tumor Effects of TRAIL-Expressing Mesenchymal Stromal Cells in a Mouse Xenograft Model of Human Mesothelioma

, 2015
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment which contributes to tumor initiation, development, severity, and propagation. We reasoned that
Sage, E, Janes, SM
core  

Assessment of Dried Plasma Spots (DPS) as an Appropriate Sample Matrix for the Measurement of Circulating Calretinin, a Biomarker for Mesothelioma—A Proof‐Of‐Concept Study

Journal of Clinical Laboratory Analysis, EarlyView.
In this proof‐of‐concept study calretinin as a biomarker for mesothelioma was evaluated using filter cards, i.e., dried plasma spots (DPS) as an alternative sample matrix. After drying, calretinin was reconstituted and determined using ELISA. Calretinin could be reliably determined and the performance of calretinin is slightly improved in comparison to
Jan Gleichenhagen, Nina Kaiser, Thomas Brüning, Georg Johnen, Daniel G. Weber   +4 more
wiley   +1 more source