Results 61 to 70 of about 64,353 (271)

Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI‐1) Deficient Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration: A Case Report

Diagnostic Cytopathology, EarlyView.
ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang, Juandi Liu, Jing Jin, Deng Pan, Lei Shao   +4 more
wiley   +1 more source

Treatment and survival of patients with esophageal and gastric cancer in the Netherlands and Belgium: A population‐based comparison

International Journal of Cancer, EarlyView.
What's New? Marked differences in esophageal and gastric cancer survival rates exist between the Netherlands and Belgium, for reasons that remain unclear. In this study, the authors in‐vestigated these differences and attempted to identify contributing factors.
Benthe H. Doeve, Steven C. Kuijper, Geert Silversmit, Lien van Walle, Philippe Nafteux, Camiel Rosman, Pauline A. J. Vissers, Paul Jeene, Laurens V. Beerepoot, Sarah Derks, Amine Karimi, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven, Rob H. A. Verhoeven   +13 more
wiley   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

MONITORING OF MESOTHELIOMA IN SOUTHERN BRAZIL: A SITUATION TO BE INVESTIGATED

Cogitare Enfermagem, 2017
Brazil is one of the world’s greatest producers of chrysotile, but the occurrence of mesothelioma is apparently low. However, identification of cases of mesothelioma is difficult due to errors of diagnosis and registries of deaths.
Francisco José Koller, Leila Maria Mansano Sarquis, Maria de Fátima Mantovani, Fernanda Moura D’Almeida Miranda, Dario Consonni, Carolina Mensi   +5 more
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Intercellular Communication in Malignant Pleural Mesothelioma: Properties of Tunneling Nanotubes

Frontiers in Physiology, 2014
Malignant pleural mesothelioma is a particularly aggressive and locally invasive malignancy with a poor prognosis despite advances in understanding of cancer cell biology and development of new therapies.
Justin William Ady, Snider eDesir, Snider eDesir, Venugopal eThayanithy, Rachel Isaksson Vogel, André L. Moreira, Robert John Downey, Yuman eFong, Katia eManova-Todorova, Malcolm A. S. Moore, Emil eLou   +10 more
doaj   +1 more source

Peripheral versus Marrow Lipidomics in Patients with Severe Aplastic Anemia: Potential Indicators for Early Immunosuppressive Treatment Response

Lipids, EarlyView.
ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun, Yilei Hong, Yaonan Hong, Chuanao Xin, Qi Liu, Huijin Hu, Yingying Shen, Ying Chen, Shan Liu, Yiping Shen, Yuhong Zhou, Dijiong Wu   +11 more
wiley   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Peritoneal mesothelioma

Translational Lung Cancer Research, 2020
Malignant peritoneal mesothelioma (MPM) is a rare and lethal disease of the peritoneal lining, with high variability in biologic aggressiveness. Morbidity and mortality of the disease are related to progressive locoregional effects within the abdominal cavity, such as distention, pain, early satiety, and decreased oral intake that can ultimately lead ...
Greenbaum, Alissa, Alexander, H. Richard
openaire   +3 more sources

Integrative eQTL and Mendelian randomization analysis reveals key genetic markers in mesothelioma

Respiratory Research
Background Mesothelioma is a rare cancer that originates from the pleura and peritoneum, with its incidence increasing due to asbestos exposure. Patients are frequently diagnosed at advanced stages, resulting in poor survival rates.
Jinsong Li, Xingmeng Wang, Yaru Lin, Zhengliang Li, Wei Xiong   +4 more
doaj   +1 more source