Epithelial-Mesenchymal Plasticity in the D-Meso-Sonobe Mesothelioma Cell Line: A Putative Model of Epithelial-Mesenchymal Transition in Mesothelioma. [PDF]
EMT plasticity of D‐Meso‐Sonobe cells D‐Meso‐Sonobe cells exhibited epithelioid features in passage culture at approximately 60% confluence (upper left), but became spindle‐cell mesenchymal cells after continuous full confluent culturing (upper right). LOXL1 immunoreactivity was found at the invasion front near muscle cells, while minimum staining was ...
Okubo H+4 more
europepmc +2 more sources
Anti-Tumor Effects of TRAIL-Expressing Mesenchymal Stromal Cells in a Mouse Xenograft Model of Human Mesothelioma [PDF]
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment which contributes to tumor initiation, development, severity, and propagation. We reasoned that
Janes, SM, Sage, E
core
A comparison of the results from intra-pleural and intra-peritoneal studies with those from inhalation and intratracheal tests for the assessment of pulmonary responses to inhalable dusts and fibres. [PDF]
The aim of this paper is to compare results from inhalation studies with those from intraperitoneal and intrapleural tests, where available, for a number of fibrous and particulate test materials.
Bevan, Ruth+2 more
core +1 more source
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling+4 more
wiley +1 more source
Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu+6 more
wiley +1 more source
Early Contrast Enhancement: a novel Magnetic Resonance Imaging biomarker of pleural malignancy [PDF]
Introduction: Pleural Malignancy (PM) is often occult on subjective radiological assessment. We sought to define a novel, semi-objective Magnetic Resonance Imaging (MRI) biomarker of PM, targeted to increased tumour microvessel density (MVD) and ...
Alexander, Laura+10 more
core +1 more source
In this matched cohort study, total costs associated with robotic pancreatectomy were significantly lower than those associated with open pancreatectomy. High intraoperative costs associated with robotic pancreatectomies can be mitigated by other hospital related factors such as length of stay, number of medication prescriptions, and standardization of
Heather G. Lyu+9 more
wiley +1 more source
Adenomatoid mesothelioma arising from the diaphragm: a case report and review of the literature
Background Adenomatoid mesothelioma is a rare subtype of malignant mesothelioma that can be confused with adenomatoid tumors, which are classified as benign.
Kenta Kawabe+12 more
doaj +1 more source
The diagnostic performance of routinely acquired and reported computed tomography imaging in patients presenting with suspected pleural malignancy [PDF]
Objectives: Contrast-enhanced computed tomography (CT) provides essential cross-sectional imaging data in patients with suspected pleural malignancy (PM). The performance of CT in routine practice may be lower than in previously reported research. We
Alexander, Laura+4 more
core +1 more source
The contribution of extracellular RNA and its derived biomaterials in disease management
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei+8 more
wiley +1 more source