Results 121 to 130 of about 1,626,022 (379)

Synthesis and Turnover of Mitochondrial Ribonucleic Acid in HeLa Cells: the Mature Ribosomal and Messenger Ribonucleic Acid Species Are Metabolically Unstable [PDF]

, 1981
The synthesis rates and half-lives of the individual mitochondrial ribosomal ribonucleic acid (RNA) and polyadenylic acid-containing RNA species in HeLa cells have been determined by analyzing their kinetics of labeling with [5-^3H]-uridine and the ...
Attardi, Giuseppe, Gelfand, Robert
core  

Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]

, 2019
The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant, Anderson, Andersson, Badawy, Balwani, Bissell, Bissell, Bloomer, Bonkovsky, Bonkovsky, Bonkovsky, Bonkovsky, Bonkowsky, Bonkowsky, Bonkowsky, Bylesjo, Chen, D’Avola, Ferrer, Glueck, Handschin, Jeans, Lambrecht, Lane, Marsden, McGuire, Pallet, Sardh, Sardh, Shen, Singal, Stein, Stewart, Tchernitchko, Wahlin, Watson, Watson, Willandt, Wu, Yarra, Yasuda   +40 more
core   +1 more source

Association Between the BNT162b2 Messenger RNA COVID-19 Vaccine and the Risk of Sudden Sensorineural Hearing Loss [PDF]

, 2022
Yoav Yanir, Ilana Doweck, Rana Shibli, Ronza Najjar‐Debbiny, Walid Saliba   +4 more
openalex   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Early changes of placenta-derived messenger RNA in maternal plasma – potential value for preeclampsia prediction?

Romanian Journal of Laboratory Medicine, 2015
Objective: the pourpose of the study was to determine if there are any differences between placenta derived plasmatic levels of messenger RNA in normal and future preeclamptic pregnancies and if these placental transcripts can predict preeclampsia long ...
Surugiu Sebastian, Chis Adina, Mare Codruta, Matei Horea, Stamatian Florin   +4 more
doaj   +1 more source

Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung

Nature Materials, 2022
L. Rotolo, D. Vanover, Nicholas C. Bruno, H. Peck, C. Zurla, J. Murray, Richard K. Noel, L. O'farrell, M. Araínga, Nichole Orr-Burks, J. Joo, Lorena C S Chaves, Younghun Jung, Jared P Beyersdorf, S. Gumber, R. Guerrero-Ferreira, Santiago Cornejo, M. Thoresen, A. Olivier, Katie M. Kuo, J. Gumbart, Amelia R. Woolums, F. Villinger, Eric R. Lafontaine, R. J. Hogan, M. G. Finn, P. Santangelo   +26 more
semanticscholar   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Expression of Colony-Stimulating Factor-1 (CSF-1) Messenger RNA in Human Endometrial Glands during the Menstrual Cycle: Molecular Cloning of a Novel Transcript That Predicts a Cell Surface Form oF CSF-1 [PDF]

, 1991
S. Pampfer, Siamak Tabibzadeh, Fen-Chi Chuan, Jeffrey W. Pollard   +3 more
openalex   +1 more source

Chemical synthesis of super messenger RNA medicine

, 2023
Mizuki Tada, Naoko Abe, Hiroshi Abe
openalex   +2 more sources

Nanoparticle‐Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer‐Associated Cachexia (Small 44/2022) [PDF]

, 2022
Tetiana Korzun, Abraham S. Moses, Jeonghwan Kim, Siddharth Patel, Canan Schumann, Peter R. Levasseur, Parham Diba, Brennan Olson, Katia G. de Oliveira Rebola, Mason A. Norgard, Youngrong Park, Ananiya A. Demessie, Yulia Eygeris, Vladislav Grigoriev, Subisha Sundaram, Tanja Pejović, Jonathan R. Brody, Olena Taratula, Xinxia Zhu, Gaurav Sahay, Daniel L. Marks, Oleh Taratula   +21 more
openalex   +1 more source