Results 131 to 140 of about 190,885 (290)

Combining PIM‐2 and PARP1 Inhibitors Induces MICA Expression on Multiple Myeloma Cells to Activate NK Cells through NKG2D Binding

Advanced Science, EarlyView.
The findings suggest that the combination of PIM‐2 and PARP1 inhibitors can induce MICA expression on MM cells, thereby activating NK cells through NKG2D binding. This process may restore NK cell function and serve as a potential therapeutic approach for MM patients. Abstract While immunogenic death in tumor cells activates specific anti‐tumor T cells,
Zhaoyun Liu, Wenhui Lei, Xiaohan Liu, Hui Liu, Kai Ding, Jia Song, Rong Fu   +6 more
wiley   +1 more source

Chromatin measurements reveal contributions of synthesis and decay to steady‐state mRNA levels

Molecular Systems Biology, 2012
Messenger RNA levels in eukaryotes are controlled by multiple consecutive regulatory processes, which can be classified into two layers: primary transcriptional regulation at the chromosomal level and secondary, co‐ and post‐transcriptional regulation of
Sylvia C Tippmann, Robert Ivanek, Dimos Gaidatzis, Anne Schöler, Leslie Hoerner, Erik van Nimwegen, Peter F Stadler, Michael B Stadler, Dirk Schübeler   +8 more
doaj   +1 more source

DEMONSTRATION OF THE MESSENGER ROLE OF VIRAL RNA [PDF]

, 1962
Akira Tsugita, H. Fraenkel‐Conrat, M Nirenberg, Johannes Matthaei   +3 more
openalex   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

TaPPR13, a Pentatricopeptide Repeat Protein Gene Activated by TaBZR2, Confers Drought Stress Tolerance by Enhancing the Antioxidant Defense System and Promoting Retrograde Signaling in Wheat (Triticum aestivum)

Advanced Science, EarlyView.
TaPPR13, a PPR protein family gene in wheat is activated by TaBZR2 to enhance drought stress tolerance and photosynthetic capacity. It achieves this by interacting with TaAOR1 and TaSIG5 to improve antioxidant defense and regulate chloroplast gene expression. Abstract The wheat (Triticum aestivum) brassinazole‐resistant 2 (TaBZR2) gene is identified as
Ze‐Hao Hou, Wei‐Jun Zheng, Lei Zheng, Jing‐Yue Wang, Shuang‐Xi Zhang, Ji‐Tong Wei, Shu‐Hui Yang, Yuan‐Chen Jiao, Wen‐Jing Cheng, Tai‐Fei Yu, Xiao‐Fei Ma, Jing‐Na Ru, Yong‐Wei Liu, Xin‐You Cao, Jun Chen, Yong‐Bin Zhou, Ming Chen, Li‐Hui Li, You‐Zhi Ma, Xiao‐Jun Nie, Zhao‐Shi Xu   +20 more
wiley   +1 more source

Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma

Rare Tumors, 2018
Background: Previous studies have shown that aberrant activation of the Wnt/β-catenin pathway is associated with many malignant neoplasms. This includes some soft-tissue sarcoma phenotypes, most notably synovial sarcoma, implicating potential targets for
Laurence M Briski, Dafydd G Thomas, Rajiv M Patel, Elizabeth R Lawlor, Rashmi Chugh, Jonathan B McHugh, David R Lucas   +6 more
doaj   +1 more source

Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. [PDF]

, 2020
Background & aimsBiotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis.
Cahalan, Michael D, Hwang, Michael, Nakasaki, Manando, Sabui, Subrata, Said, Hamid M, Skupsky, Jonathan   +5 more
core  

THE SYNTHESIS OF MESSENGER RNA WITHOUT PROTEIN SYNTHESIS IN NORMAL AND PHAGE-INFECTED THYMINELESS STRAINS OF ESCHERICHIA COLI [PDF]

, 1963
Shira Cohen, Masahiro Sekiguchi, Jerry Stern, Hazel D. Barner   +3 more
openalex   +1 more source

Accelerating Sono‐Piezoelectric Charge Transport for Antibacterial Therapy and Bone Regeneration by Metal‐Deficient TiO2 Spin‐Polarization Effect

Advanced Science, EarlyView.
The deficient TiO2 (DTO) and Barium titanate (BTO) heterojunction treats osteomyelitis through SDT. The spin‐polarization effect induced by the unpaired spin electrons in Ti atoms can expedite the transfer of ultrasonic piezoelectric charges in BTO, enhancing surface sonocatalytic efficiency.
Chaofeng Wang, Shuilin Wu, Congyang Mao, Liguo Jin, Hanpeng Liu, Yufeng Zheng, Chunyong Liang, Shengli Zhu, Zhaoyang Li, Hui Jiang, Xiangmei Liu   +10 more
wiley   +1 more source

Asymmetry of Calculated Messenger RNA [PDF]

, 1965
José Tohá
openalex   +1 more source