Results 181 to 190 of about 312,118 (258)

Enhanced Skin Wound Healing Through Chemically Modified Messenger RNA Encoding Epidermal Growth Factor (EGF). [PDF]

Int Wound J
Hu H, Sheng Q, Yang F, Wu X, Zhang Y, Wu S, Liu Y, Hu N, Fu C, Leong J, Deng R, Jiang Z, Chen J, Wang Z, Chen C, Chen F, Luo Y, Zeng Y, Yu Y, Xie H, Wang G, Zou L.   +21 more
europepmc   +1 more source

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

Biological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief, Sandra Bouwhuis, Anja Globig, Anne Günther, Wouter Courtens   +4 more
wiley   +1 more source

Immunoinformatic development of a multiepitope messenger RNA vaccine targeting lipoate protein ligase and dihydrolipoamide dehydrogenase proteins of <i>Mycoplasma bovis</i> in cattle. [PDF]

Vet World
Al-Fetly DR, Alsallami D, Alsultan A.
europepmc   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling. [PDF]

Chemistry
D'Anna L, Froux A, Rainot A, Spinello A, Perricone U, Barbault F, Grandemange S, Barone G, Terenzi A, Monari A.   +9 more
europepmc   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

Biotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan, Fatemeh Najafi, Ziqiao Wang, Andrew L. Zydney   +3 more
wiley   +1 more source

The effect of sleep and shift work on the primary immune response to messenger RNA-based COVID-19 vaccination. [PDF]

J Sleep Res
Brouwers TMJ, Çobanoğlu ÜG, Geers D, Rietdijk WJR, Gommers L, Bogers S, Lammers GJ, van der Horst GTJ, Chaves I, GeurtsvanKessel CH, Koch BCP, de Vries RD, van Baarle D, van der Kuy HM, Lammers-van der Holst HM.   +14 more
europepmc   +1 more source

PERFECTA Loaded Lipid Cubosomes for 19F‐MRI: Physico‐Chemical Characterization

Chemistry – A European Journal, EarlyView.
Phytantriol‐based cubosomes loaded with PERFCTA, a fluorinated MRI probe, were developed as promising systems for imaging and drug delivery. The nanoparticles showed high PERFECTA encapsulation efficiency, strong fluorine MRI signals, and optimal colloidal stability in biological media.
Pietro Milesi, Beatrice Lucia Bona, Cristina Chirizzi, Marco Campanile, Pompea Del Vecchio, Marc Schmutz, Valerie Sartor, Debora Berti, Pierangelo Metrangolo, Francesca Baldelli Bombelli, Barbara Lonetti   +10 more
wiley   +1 more source

A Case of Rapid Transformation of a Nail Matrix Nevi to Melanoma After Messenger RNA COVID-19 Vaccine: A Cause or a Coincidence? [PDF]

Cureus
Farhat M, Zouein J, Abou Khater J, Sarkis AS, Helou J.   +4 more
europepmc   +1 more source

Raman Optical Activity as a Tool to Monitor Polynucleotide Conformation in Solutions

Chemistry – A European Journal, EarlyView.
Raman optical activity (ROA) studies of nucleic acids have been hindered by limited computational tools to link the spectra to the structure. The study shows that accurate density functional simulations are possible for model nucleotides, bringing more information about molecular geometry and dynamics in solutions.
Mohammed Siddhique Para Kkadan, Josef Kapitán, Jiří Kessler, Ondřej Zapletal, Valery Andrushchenko, Petr Bouř   +5 more
wiley   +1 more source