Results 211 to 220 of about 1,593,615 (383)

Advances in miRNA research: Unraveling the complexities of gene regulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley   +1 more source

Three decades of messenger RNA vaccine development

open access: yesNano Today, 2019
Rein Verbeke   +3 more
semanticscholar   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang   +5 more
wiley   +1 more source

Optoregulated mRNA Delivery Controls Pleiotropic Immune Signaling for Tumor‐Targeted Therapy

open access: yesAngewandte Chemie, EarlyView.
A light‐induced transfection system (LITS) was designed to precisely control the delivery of mRNA, achieving spatiotemporal de‐coupling of the pleotropic inflammatory and tolerogenic signals of interleukin‐2 to conduct safe eradication of tumors. Abstract Spatiotemporal control of protein expression remains a critical challenge in messenger RNA (mRNA ...
Pengwen Chen   +7 more
wiley   +2 more sources

Physicochemical and functional assessment of messenger RNA 5'Cap-end impurities under forced degradation conditions. [PDF]

open access: yesMol Ther Nucleic Acids
Hutchinson J   +14 more
europepmc   +1 more source

Lipid nanoparticles for delivery of messenger RNA to the back of the eye.

open access: yesJournal of Controlled Release, 2019
Siddharth Patel   +4 more
semanticscholar   +1 more source

Beta Thalassemia and Translation of Globin Messenger RNA

open access: green, 1971
David G. Nathan   +3 more
openalex   +1 more source

Vitamin D‐induced mechanisms in cancer prevention and therapy: Recent advances and future opportunities

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Vitamin D, traditionally known to promote calcium and bone health, is being explored for its role in cancer prevention and treatment through its influence on cell proliferation, differentiation, apoptosis, and immune response. The vitamin D receptor (VDR) regulates gene expression and interacts with key signaling pathways such as Wnt/β‐catenin, MAPK ...
D. Prasanth   +10 more
wiley   +1 more source

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