Results 21 to 30 of about 1,216,747 (291)

HIV mRNA Vaccines—Progress and Future Paths

open access: yesVaccines, 2021
The SARS-CoV-2 pandemic introduced the world to a new type of vaccine based on mRNA encapsulated in lipid nanoparticles (LNPs). Instead of delivering antigenic proteins directly, an mRNA-based vaccine relies on the host’s cells to manufacture protein ...
Zekun Mu   +2 more
doaj   +1 more source

The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance

open access: yesTechnology in Cancer Research & Treatment, 2020
RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS   +4 more
doaj   +1 more source

Co-regulatory network of transcription factor and microrna: A key player of gene regulation

open access: yesBiomedical and Biotechnology Research Journal, 2021
Transcription factor (TF) and microRNA (miRNA) interaction plays a vital role in the regulation of biological networks. TFs and miRNAs control the gene expression: TF at transcriptional level by affecting the messenger RNA (mRNA) transcription and miRNA ...
Akshara Pande
doaj   +1 more source

Pseudo-messenger RNA: phantoms of the transcriptome. [PDF]

open access: yesPLoS Genetics, 2006
The mammalian transcriptome harbours shadowy entities that resist classification and analysis. In analogy with pseudogenes, we define pseudo-messenger RNA to be RNA molecules that resemble protein-coding mRNA, but cannot encode full-length proteins owing
Martin C Frith   +12 more
doaj   +2 more sources

From Viral Vaccines to Messenger RNA Vaccines

open access: yesPakistan Journal of Medicine and Dentistry, 2020
Today, the swiftness of epidemics of infectious disease is alarming. To date vaccines have been an enormous success for not only preventing but completely eradicating a number of malicious infectious disease like small pox, rubella, mumps, measles and ...
Saeeda Baig, Zoha Asghar
doaj   +1 more source

RNA-specific ribonucleotidyl transferases [PDF]

open access: yes, 2007
RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W.   +5 more
core   +1 more source

Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p

open access: yesTechnology in Cancer Research & Treatment, 2020
This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer.
Ziqi Peng BM, Boyang Xu BM, Feng Jin MD
doaj   +1 more source

Cotranslational microRNA mediated messenger RNA destabilization

open access: yeseLife, 2016
MicroRNAs are small (22 nucleotide) regulatory molecules that play important roles in a wide variety of biological processes. These RNAs, which bind to targeted mRNAs via limited base pairing interactions, act to reduce protein production from those ...
Trinh To Tat   +4 more
doaj   +1 more source

Xp54 and related (DDX6-like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation [PDF]

open access: yes, 2006
The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational ...
Weston, A, Sommerville, John
core   +1 more source

Vaccines against Coronavirus Type 19: An Overview [PDF]

open access: yesAl-Anbar Medical Journal, 2023
Vaccines are biological agents that provide immunity against certain diseases [1]. Vaccination is an effective technique for prevention of infection and control outbreak of a wide range of infectious diseases (https://apps.who.int/iris/handle/10665 ...
Makwan Abdulkareem
doaj   +1 more source

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