Results 31 to 40 of about 1,613,624 (375)

Lymph node CXCL17 messenger RNA: A new prognostic biomarker for colon cancer

open access: yesTumor Biology, 2018
Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as ...
Yomna Rashad   +7 more
doaj   +1 more source

Differentially Expressed mRNA in Streptozotocin-Induced Diabetic Bladder Using RNA Sequencing Analysis [PDF]

open access: yesInternational Neurourology Journal, 2023
Purpose To detect elements governing the pathogenesis of diabetic cystopathy (DC), mRNA sequencing was carried out for bladder tissues from normal rats and those with induced diabetes mellitus (DM).
Jae Heon Kim   +3 more
doaj   +1 more source

Human THO–Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability [PDF]

open access: yes, 2017
R-loops, formed by co-transcriptional DNA–RNA hybrids and a displaced DNA single strand (ssDNA), fulfill certain positive regulatory roles but are also a source of genomic instability.
Aguilera López, Andrés   +5 more
core   +1 more source

Knockdown of FLT4, Nup98, and Nup205 cellular genes as a suppressor for the viral activity of Influenza A/WSN/33 (H1N1) in A549 cell culture

open access: yesТонкие химические технологии, 2022
Objectives. To evaluate the effect of cellular genes FLT4, Nup98, and Nup205 on the reproduction of the influenza A virus in A549 human lung cancer cell line.Methods.
E. A. Pashkov   +11 more
doaj   +1 more source

MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data. [PDF]

open access: yes, 2017
Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly facilitated the study of tRFs.
Loher, Phillipe   +2 more
core   +2 more sources

Identification and Characterization of mRNA and lncRNA Expression Profiles in Age-Related Hearing Loss [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2023
Objectives Age-related hearing loss (ARHL), or presbycusis, is caused by disorders of sensory hair cells and auditory neurons. Many studies have suggested that the accumulation of mitochondrial DNA damage, the production of reactive oxygen species, noise,
Janghyun Kim   +5 more
doaj   +1 more source

The importance of circulating tumor products as „liquid biopsies” in colorectal cancer [PDF]

open access: yes, 2018
Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Calborean, Veronica   +6 more
core   +4 more sources

A small RNA response at DNA ends in Drosophila [PDF]

open access: yes, 2012
Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Böttcher, Romy   +2 more
core   +1 more source

The emerging role of RNA modifications in the regulation of mRNA stability

open access: yesExperimental and Molecular Medicine, 2020
Gene activity: the significance of RNA modification Messenger RNA molecules play their key role in directing the manufacture of proteins via translating the genetic information in DNA.
Sung Ho Boo, Yoon Ki Kim
doaj   +1 more source

Improper preanalytical processes on peripheral blood compromise RNA quality and skew the transcriptional readouts of mRNA and LncRNA

open access: yesFrontiers in Genetics, 2023
Genetic and epigenetic reprogramming caused by disease states in other tissues is always systemically reflected in peripheral blood leukocytes (PBLs).
Yinli He   +10 more
doaj   +1 more source

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