Results 51 to 60 of about 297,584 (166)

The Future of mRNA Platforms: Strategic Pause or Premature Pivot? [PDF]

open access: yesIranian Journal of Medical Sciences
The last month’s decision by the U.S. Department of Health and Human Services (HHS) to withdraw nearly $500 million from mRNA vaccine research and development (R&D) has aroused concern in the scientific and medical communities.
Manica Negahdaripour
doaj   +1 more source

Insertion of a G-quadruplex or hairpin structure into the 5' UTR or poly(A) sequences reduces translation efficiency of the encephalomyocarditis virus internal ribosome entry site: a preclinical in vitro study [PDF]

open access: yesThe Ewha Medical Journal
Purpose Internal ribosome entry site (IRES) elements, present in both viral and cellular messenger RNAs (mRNAs), facilitate cap-independent translation by recruiting ribosomes to internal regions of mRNA.
Yun Ji Kim, So-Hee Hong
doaj   +1 more source

Early changes of placenta-derived messenger RNA in maternal plasma – potential value for preeclampsia prediction?

open access: yesRomanian Journal of Laboratory Medicine, 2015
Objective: the pourpose of the study was to determine if there are any differences between placenta derived plasmatic levels of messenger RNA in normal and future preeclamptic pregnancies and if these placental transcripts can predict preeclampsia long ...
Surugiu Sebastian   +4 more
doaj   +1 more source

History of Micrornas: From Gene Controlling Development of Nematodes to a Promising Tool for Molecular Therapy

open access: yesActa Medica Martiniana
MicroRNAs are short, single-stranded RNA molecules that typically consist of a 22-nucleotide sequence. Despite their small size, these molecules play an essential role in every type of human cell – regulation of gene expression on post-transcriptional ...
Dusan Brany
doaj   +1 more source

1377 Messenger RNA nanoparticles targeting fusion-driven malignancies

open access: yesJournal for ImmunoTherapy of Cancer, 2023
Leighton Elliott   +5 more
doaj   +1 more source

Urinary mRNA biomarkers for the noninvasive diagnosis of calcineurin inhibitor toxicity in kidney transplant recipients with graft dysfunction: a retrospective study

open access: yesClinical Transplantation and Research
Background : Calcineurin inhibitor (CNI) toxicity is a significant cause of graft dysfunction in kidney transplant recipients, yet distinguishing it from acute rejection (AR) and acute tubular necrosis (ATN) remains challenging.
Jihyun Baek   +13 more
doaj   +1 more source

Discrimination of messenger RNA [PDF]

open access: yesFEBS Letters, 1978
Herrlich, Peter, Schweiger, Manfred
openaire   +2 more sources

Transient dermatomyositis-like reaction following COVID-19 messenger RNA vaccination

open access: yesJAAD Case Reports, 2023
Rodrigo A. Gutierrez, BS   +3 more
doaj   +1 more source

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