A Case of Unresectable Ampulla of Vater Carcinoma Successfully Treated with Conversion Surgery Following Sequential Systemic Chemotherapy Including Durvalumab. [PDF]
Araki T +13 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Lymph Node Metastases in Head and Neck Squamous Cell Carcinoma: The Association with Tumor Stage and Primary Tumor Location. [PDF]
Chloupek A, Grab P, Jurkiewicz D.
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
PD-1 inhibitor combined with chemoradiotherapy in two cases of ovarian cancer brain metastases: a case report. [PDF]
Li Y, Xia Y, Wang L, Liu X, Du Z.
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Metástases ósseas no câncer de mama: revisão dos achados nos exames diagnósticos por imagem
O câncer de mama é a neoplasia maligna mais frequente nas mulheres mundialmente, depois do de pele não melanoma. Nas últimas décadas, avanços no diagnóstico precoce e no tratamento conduziram a uma maior taxa de sobrevida nesse panorama.
Bastos, Isabelle Cristina de Mattos
core
Múltiplas Metástases Intracardíacas – Um Coração Rosário [PDF]
Mariana Tinoco +5 more
doaj +1 more source
Radiation therapy plus osimertinib <i>vs</i> osimertinib alone in epidermal growth factor receptor mutated non-small cell lung cancer: A systematic review. [PDF]
Javed M +14 more
europepmc +1 more source

