Results 141 to 150 of about 413,432 (237)

Clinical and molecular features associated with the presence of brain metastases and survival in patients with advanced thyroid cancer. [PDF]

Oncologist
Barron CC, Megid TBC, Deng Y, Sugumar V, Ladak S, Mesci A, Yan M, Lukovic J, Krzyzanowska MK, Sawka AM, Mete O, Ma LX.   +11 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

PET-MR Examination in Diagnosing Bone Metastases in Prostate Cancer. [PDF]

Cancer Manag Res
Su X, Li K, Wang J, Jiang Z, Shan L.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Adenocarcinoma de corpo e cauda do pâncreas com metástases hepáticas em paciente idosa: relato de caso

O câncer de pâncreas é uma neoplasia agressiva, frequentemente diagnosticada em estágios avançados devido à apresentação inicial inespecífica, como dor abdominal, náuseas, inapetência e perda de peso.
Menezes, Lucas de Gouveia Pestana Travassos de, Canedo, Paulo José Pouparina, Waridel, Débora, Martines, Brenda, Rocha, Edson Gabriel, Frati, Rodrigo   +5 more
core   +1 more source

Cervical Lymph Node Metastasis Patterns and Diagnostic Accuracy of Preoperative Staging in Oral Squamous Cell Carcinoma. [PDF]

Cancers (Basel)
Neuhaus MT, Weniger G, Papazacharias E, Fenske F, Jehn P, Lentge F, Korn P, Gellrich NC, Zimmerer R.   +8 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Avaliação da eficácia da radiocirurgia estereotáxica no tratamento de metástases cerebrais: análise retrospectiva de resultados clínicos

Introdução: As metástases cerebrais representam uma complicação frequente em pacientes com câncer, influenciando substancialmente a morbi-mortalidade e a qualidade de vida.
Rodrigues, Lucas Messias Caze, Ferreira, Tainan Gomes, Silva, Renato Rego da, Alencar, Eduardo Lopes Carreiro de, Sauer, Vitória Picinini da Silva, Lins, Gabriel Henrique Albuquerque, Ferraz, João Guilherme Dorneles, Gomes, Luara Bela Rocha, Cordeiro Júnior, Carlos Wagner Leal   +8 more
core  

Metástases cerebrais em carcinoma diferenciado de tireoide : características clínicas, tratamento e prognóstico [PDF]

Introdução: As metástases cerebrais decorrentes de carcinomas diferenciados de tireoide (CDT) são raras, havendo dados limitados na literatura para orientar seu manejo.
Baumgarten, Matheus Wohlfahrt
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source