Results 91 to 100 of about 845,740 (255)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Caracterización clínica epidemiológica de pacientes operados de tumores raquimedulares

Revista Cubana de Medicina Militar, 2019
Introducción: Los tumores raquimedulares son la mayor causa de morbilidad y mortalidad entre pacientes con afecciones oncológicas y representan aproximadamente del 10 al 15 % de todos los tumores del sistema nervioso central.
Alpha Singuepire, Héctor Figueredo Acosta, Kirenia Fonseca Sosa   +2 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Biomarcadores para determinar factores de riesgo y complicaciones postquirúrgicas en pacientes con gastrectomía. Revisión de literatura

Ciencia & Salud
En la actualidad se cuenta con diversos enfoques y medidas terapéuticas para un paciente con cáncer gástrico. La gastrectomía es uno de los procedimientos quirúrgicos más utilizado en la práctica clínica para su tratamiento.
Luis Miguel Flórez Castaño
doaj   +1 more source

Oligodendroglioma anaplásico metastático

Galicia Clínica, 2018
Metastization from a brain primary tumor is a rare event. The mechanisms of metastization and the best treatment approach are still unknown. Knowledge is, so far, mostly based on case reports.
Ana Sofia Patrão, Inês Sequeira, Manuel Jacóme, Joaquina Maurício   +3 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Tumores del tracto urinario [PDF]

, 1988
Se revisa un total de 12 tumores del tracto urinario, diagnosticados en un periodo de 8 años. Se expone el diagnóstico, tratamiento y seguimiento de los casos que no fueron sacrificados.The author shows a total number of twelve urinary tract tumors ...
Durall Rivas, Ignacio
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Carcinoma diferenciado de tiroides como hallazgo incidental tras cirugía tiroidea por patología benigna [PDF]

, 2019
La incidencia del carcinoma diferenciado de tiroides (CDT) está aumentando en los últimos años. Una proporción significativa se consideran hallazgos incidentales de estudios histológicos de cirugía tiroidea, sin manifestaciones clínicas ni radiológicas ...
Alaejos Pérez, María Isabel, Barreda Pérez, Laura   +1 more
core  

Malignant pheochromocytoma treated with minimally invasive surgery [PDF]

, 2014
Indexación: Web of Science; Scielo.Introducción: El Feocromocitoma es un tumor de células cromafines productor de catecolaminas. Su variedad maligna es muy poco frecuente.
Alemán F., Enrique, Aranguren G., Gabriel, Castillo C., Octavio A., López-Vallejo C., Jorge, Riera A., Pablo, Rodríguez J., Yáder   +5 more
core   +1 more source