Results 101 to 110 of about 856,729 (252)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Terapia breve y de emergencia para la mujer tras la mastectomía completa por cáncer de mama. [PDF]
, 2013 Midió la efectividad de la Terapia Breve y de Emergencia en la mujer tras la mastectomía completa por cáncer de mama. Identificó las consecuencias psicológicas de la mujer tras la mastectomía.
Ambrosio Zapón, Alma María +1 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Supervivencia y seguimiento clínico de mujeres mastectomizadas durante una década
Medisan, 2013 Se llevó a cabo una investigación explicativa, de cohorte y aplicada, en 132 pacientes operadas por cáncer de mama, con seguimiento clínico en la consulta de Mastología del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres" de Santiago
José Manuel Ricardo Ramírez +4 more
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Tratamiento quirúrgico de las metástasis diafisarias de huesos largos en pacientes oncológicos estadio IV [PDF]
, 2014 La incidencia de enfermedad metastásica ósea se ha incrementado debido a la mayor supervivencia de los pacientes con cáncer. El esqueleto es la tercera localización mas frecuente de metástasis procedentes de tumores primarios.
Brú Pomer, Antonio +4 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Cirugía del Uruguay, 2020 Se presenta un nuevo caso de carcinoma tiroideo clínicamente inaparente revelado por su metástasis ganglionar ...
Federico Latourrette +2 more
doaj
Extended pelvic lymphadenectomy in prostate cancer: is warranted in patients at low risk? [PDF]
, 2014 Determinar la incidencia de compromiso ganglionar de acuerdo a la clasificación de riesgo de D’amico en los pacientes llevados a prostatectomía radical con linfadenectomía pélvica ampliada (LDN).
Cespedes Orrego, Carlos Arturo +4 more
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