Results 121 to 130 of about 88,730 (192)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Metástasis renal de hepatocarcinoma [PDF]

, 2003
OBJETIVO: Presentar el caso de una metástasis renal solitaria secundaria a hepatocarcinoma. MÉTODO: Describimos el caso de un paciente de 51 años que en ecografía abdominal se descubre incidentalmente una masa renal izquierda y una masa hepática.
Sanz Mayayo,E., Sáenz Medina,J., Escudero Barrilero,A., Mayayo Dehesa,T., Gómez García,I., Rodríguez-Patrón Rodríguez,R.   +5 more
core   +1 more source

El nódulo de la hermana Mary Joseph: Presentación de un caso Sister Mary Joseph's nodule presentation of one case

Revista Colombiana de Cirugía, 2004
Se presentan hallazgos anatomoclínicos del nódulo de la hermana Mary Joseph, adenocarcinoma metastático al ombligo, a propósito de una mujer hospitalizada e intervenida quirúrgicamente para corregirle una hernia umbilical.We present the pathologic ...
Jorge Mogollón Torres
doaj  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Metástasis tiroidea de tipo aneurismático

Cirugía del Uruguay, 2020
Presentado en sesión de 24 de agosto de ...
José A Piquinela, Nelson B Varela, N Toledo   +2 more
doaj  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Metástasis ósea de cáncer de próstata

, 2009
Cuatro imágenes de una metástasis ósea de un cáncer de próstata en un paciente de 66 años.Four pictures of a bone metastasis of a prostate cancer in a 66-year-old male ...
Iglesias Rozas, José Rafael, 1942-
core  

METÁSTASIS CUTÁNEA DE UN CARCINOMA DE PULMÓN SIMULANDO UN QUERATOACANTOMA

, 2013
Las metástasis cutáneas son una manifestación poco frecuente de una malignidad interna. La lesión tumoral primaria puede preceder a la metástasis, presentarse de forma concomitante o ser detectada posteriormente por los hallazgos encontrados en piel. Las
Zuluaga, María Alejandra, Martínez, Wilber Javier, Gallego, Pamela, Colmenares Roldan, Lina Maria   +3 more
core   +1 more source