Results 121 to 130 of about 856,729 (252)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Revista Colombiana de Cirugía, 2004 Se presentan hallazgos anatomoclínicos del nódulo de la hermana Mary Joseph, adenocarcinoma metastático al ombligo, a propósito de una mujer hospitalizada e intervenida quirúrgicamente para corregirle una hernia umbilical.We present the pathologic ...
Jorge Mogollón Torres
doaj
Tumores testiculares caninos : a propósito de dos casos clínicos [PDF]
, 2010 Los tumores testiculares tienen una mayor incidencia en la especie canina que en otras especies y son una patología habitual en la clínica diaria, aunque generalmente son hallazgos de la exploración física.
Cloquell, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Metástasis tiroidea de tipo aneurismático
Cirugía del Uruguay, 2020 Presentado en sesión de 24 de agosto de ...
José A Piquinela +2 more
doaj
Cáncer colorrectal. Revisión de la literatura y propuesta de protocolo [PDF]
, 2013 El cáncer colorrectal es la segunda causa de mortalidad tanto en hombres como mujeres. Se conoce que el 75% de las causas de aparición se tratan de factores extrínsecos como la dieta,todos ellos modificables y previsibles, por esto mismo se incrementa la
Martínez Rubio, Margarita
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Intervención logopédica en un paciente laringectomizado. La importancia de las asociaciones. [PDF]
, 2019 Este trabajo recoge la información recopilada sobre la intervención logopédica en pacientes laringectomizados, ejemplificado con la intervención personal llevada a cabo con un paciente operado, con una laringectomía total, y con unas características ...
Martínez Martín, Celia
core