Results 91 to 100 of about 878,108 (245)

Metástasis a pulmón: manejo individualizado [PDF]

open access: yes, 2016
ResumenEn el manejo de la enfermedad oncológica, la presentación de metástasis a pulmón se encuentra en el 20-60% a lo largo de su historia natural. Esta oscilación tan amplia obedece a la histología del tumor, comportamiento biológico, etapa clínica al ...
Herrera Gómez, Ángel   +3 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Metástasis en el aparato locomotor [PDF]

open access: yes
La metástasis ósea (MTS ósea) es la diseminación hematógena de un tumor maligno. El tejido hepático, óseo y pulmonar son las principales localizaciones de las metástasis por carcinoma.
Fernández, Claudio Alfredo   +2 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Meningioma con metástasis

open access: yes, 2009
Dos imágenes de un meningioma con metástasis en una paciente de 50 años.Two pictures of a meningioma with metastasis in a 50-year-old male ...
Iglesias Rozas, José Rafael, 1942-
core  

Tratamiento quirúrgico de las metástasis del cáncer renal [PDF]

open access: yes, 2009
La extirpación completa de lesiones metastásicas pueden contribuir a mejorar el pronóstico clínico del cáncer renal. Hoy en día, se acepta que la extirpación quirúrgica de las metástasis solitarias para los pacientes con cáncer renal es la única ...
Ruiz-Cerdá,José L.   +1 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Metástasis cerebral y rabdomiosarcoma

open access: yes, 2009
Tres imágenes de un cerebro afectado por metástasis cerebral y rabdomiosarcoma.Three pictures of a brain affected by cerebral metastasis and ...
Iglesias Rozas, José Rafael, 1942-
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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