A Case of a Rare Testicular Tumor With Synchronous Malignancy
ABSTRACT Introduction Leydig cell tumors are an uncommon malignancy accounting for 1%–2% of all testicular tumors. Synchronous, non‐testicular malignancy is a rare finding. Case Presentation A 51‐year‐old male presented with left testicular pain, and a scrotal ultrasound revealed a testicular mass.
Leslie Hoyt +4 more
wiley +1 more source
Diagnosis, treatment, and long-term follow-up of a 13-year-old boy with a testicular mixed germ cell tumor (yolk sac tumor and embryonal carcinoma): a case report and literature review. [PDF]
Yang J, Lai J, Zheng S, Tang H.
europepmc +1 more source
Highlight Seo and colleagues investigated the association of preoperative natural tooth count and posterior teeth occlusion with overall survival after pancreatic cancer resection. Having ≤20 teeth was independently associated with worse survival, whereas occlusion was not.
Kaoru Seo +8 more
wiley +1 more source
Sequential Photodynamic Therapy and Electrochemotherapy for Bilateral Palpebral Squamous Cell Carcinoma in a Cat: A Case Report. [PDF]
Guimarães TG +6 more
europepmc +1 more source
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
Neuroendocrine Tumors of the Gallbladder: A Multicenter Case Series and Systematic Literature Review Indicating Predominantly Non-Aggressive Tumor Behavior and a Common Association with Cholesterol Polyps and Cholesterolosis. [PDF]
Vanoli A +24 more
europepmc +1 more source
Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh +3 more
wiley +1 more source
Immunotherapeutic Strategies for Prostate Cancer: A Comprehensive Review. [PDF]
Flores-Islas AK +7 more
europepmc +1 more source
Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
wiley +1 more source
Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source

