Results 101 to 110 of about 226,196 (309)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The Impact of Institutions on the Decision How to Decide [PDF]
The human mind is not a general problem solving machine. Instead of deliberately, consciously and serially processing the available information, men can rely on routines, rules, roles or affect for the purpose.
Christoph Engel, Elke U. Weber
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Need for regulatory revamp of private institutions
, 2016 This paper examines the need for regulatory revamp of private institutions in Singapore, many of which may not have met the regulatory requirements if strict monitoring actions were to be applied to them.
Yu, Victor Sing Ong
core +1 more source
The Status of Maritime Education and Training in Environmental Management in Uganda: An Overview
Current: The Journal of Marine EducationMaritime transport presents significant trade opportunities and economic development in Uganda and the Lake Victoria Basin. Nonetheless, maritime transportation and port activities are sources of pollutants like ballast water discharge, greenhouse gas ...
Sylvie Muwanga Tebitendwa +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Health SA Gesondheid: Journal of Interdisciplinary Health Sciences, 2013 Seventy to ninety percent of HIV-infected individuals have oral lesions that affect their quality-of-life. Caregivers play an important role in complementing the healthcare team.
Yolanda Kolisa, Olalekan Ayo-Yusuf
doaj +1 more source
, 2018 Met expectations” research into job satisfaction (Locke, 1976; Porter & Steers, 1973) has shown that the expectations employees bring to their jobs influence their overall job satisfaction. At colleges and universities, faculty job satisfaction is important because it can provide a measure of overall institutional effectiveness (Cameron, 1978), and can
openaire +3 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Indonesian Interdisciplinary Journal of Sharia EconomicsThis article discusses energy management in higher education institutions using bibliometric analysis to understand past and future research trends, so that future energy needs can be met.
Rantau Gelora Leonardo Juniko +1 more
doaj +1 more source