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Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Institutions and Industrial Revolution
We survey significant literature on the role of institutions in industrial revolution. Literature shows that institutions played an important role in facilitating technological progress and thus overcoming Malthusian stagnation.
Šenfelde, Maija, Vītola, Alise
core
Programmeerplagiaatdetectie met Marble
. In Utrecht gebruiken we bij verscheidene programmeervakken al enkele jaren een plagiaatdetector, momenteel genaamd Marble. Ik beschrijf in dit artikel hoe we met plagiaat en andere vormen van fraude omgaan in Utrecht, hoe Marble werkt en gebruikt kan ...
Jurriaan Hage +1 more
core
Column - In veel landen wordt geworsteld met de bestuurlijke aanpak van regionale ruimtelijke vraagstukken. Moet de bestuurlijke indeling worden aangepast? Zo ja,moet dat voor het hele land worden gedaan?
Zonneveld, W.A.M. (author)
core
Evaluation of Institutions in Innovation-Driven Economies
The aim of the paper is to quantitatively evaluate the quality of institutions in innovation-driven economies. We define institutions as socially approved behaviour models that restrict the rationality of an individual and constrain or encourage specific
Šenfelde, Maija, Vītola, Alise
core +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source

