Results 141 to 150 of about 226,196 (309)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Beyond Independence:The Ethics of Trustworthy Intelligence Institutions [PDF]

open access: yes
The focus of this chapter is on the relationships between intelligence institutions and other political institutions. I suggest that there is a commonly held belief that intelligence and politics ought to be independent.
Henschke, Adam; id_orcid
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Quality assurance in maritime education and training institutions

open access: yes, 1995
The dissertation is a research into the existing standards on quality and quality management systems with particular focus on quality assurance. A study is made of the different approaches to implementation of quality assurance systems and adaptation of ...
Sim, Lin Woon
core  

Fiscal Decentralisation, Democratic Institutions and Inflation

open access: yes, 2013
This study examines the role of democratic institutions in an attempt to explain the relationship between fiscal decentralisation and inflation.
Iqbal, Nasir
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Corporate governance and Shariah compliance in institutions offering Islamic financial services [PDF]

open access: yes
The structures and processes established within an institution offering Islamic financial Services (IIFS) for monitoring and evaluating Shariah compliance rely essentially on arrangements internal to the firm.
Grais, Wafik, Pellegrini, Matteo
core  

10156-MET-5 Clinical Characteristics and Prognostic Factors of Stereotactic Radiotherapy for Brain Metastases from Lung Cancer: A Multi-Institutional Study

open access: yesNeuro-Oncology Advances
Abstract Background Stereotactic irradiation (STI) has become a standard treatment in addition to whole-brain radiation therapy for metastatic brain tumors. However, real-world clinical practice and prognostic factors associated with this approach have not been fully elucidated.
Mineharu, Yohei   +11 more
openaire   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

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