Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
Commentary on methodological rigor in "Predictors of exclusive breastfeeding: a systematic review and meta-analysis". [PDF]
Kumar A +4 more
europepmc +1 more source
Multi‐Site Transfer Classification of Major Depressive Disorder: An fMRI Study in 3335 Subjects
The study proposes graph convolution network with sparse pooling to learn the hierarchical features of brain graph for MDD classification. Experiment is done on multi‐site fMRI samples (3335 subjects, the largest functional dataset of MDD to date) and transfer learning is applied, achieving an average accuracy of 70.14%.
Jianpo Su +14 more
wiley +1 more source
Efficacy and safety of anticoagulant therapy in sepsis: A systematic review and meta-analysis. [PDF]
Lu J, Zhang Z, Wang L.
europepmc +1 more source
Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang +22 more
wiley +1 more source
Mapping 50 Years of Sport Psychology-Performance Meta-Analyses: A PRISMA-ScR Scoping Review. [PDF]
Lochbaum M, Lane AM.
europepmc +1 more source
Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu +6 more
wiley +1 more source
Pre-PCI SGLT2 inhibitors and contrast-induced nephropathy in acute myocardial infarction: A meta-analysis. [PDF]
Li Y, Zhang W, Li R.
europepmc +1 more source
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source

