Results 31 to 40 of about 2,170,654 (281)

Christian ethics in the face of secularism

open access: yesVerbum et Ecclesia, 2012
This article deals with the implications of modern secularism for the concept of Christian ethics. How does the decline of Christianity in modern Western societies impede the validity of a Christian ethical approach to contemporary social issues?
Jakobus M. Vorster
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Scale Structure of Moral Adjectives

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.08 In this paper we discuss how and whether moral adjectives fit a well-known semantics for gradable adjectives. We first test whether moral adjectives are relative or absolute adjectives. The preliminary results
Federico L. G. Faroldi   +1 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Descriptive vs. normative ethics, meta-ethics, etc.; Cornell University lecture, Natural Resources 407 (1994-02-22)

open access: yes, 1994
Lecture was recorded on a Lapel Microphone, using a Cassette Tape.Descriptive vs. normative ethics, meta-ethics, logical positivism, the extent of ethical consensus, John Rawls "reflective equilibrium", teleological ethics, Alistair MacIntyre ...
Baer, Richard
core   +5 more sources

Meta-analysis of moral intelligence studies [PDF]

open access: yesمطالعات روانشناسی تربیتی, 2018
Moral intelligence is linked with work and ethics. Multiple research have examined the relationship between moral intelligence. Given that moral intelligence is the ability to distinguish right from wrong, the right choice and ultimately behavior based ...
Abolghasem Yaghoobi   +2 more
doaj   +1 more source

A Meta-Analytic Investigation of Business Ethics Instruction

open access: yes, 2009
ethics, business ethics, ethics instruction, ethics training, training effectiveness, meta-analysis,
Alison L. Antes   +8 more
core   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

open access: yesAging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara   +3 more
wiley   +1 more source

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