Results 41 to 50 of about 441,361 (299)

A critique of Kwasi Wiredu’s humanism and impartiality

open access: yesActa Academica, 2016
This article offers a critical reflection on Kwasi Wiredu’s moral theory. On the one hand, the article is concerned with the meta-ethical question regarding the nature of moral properties, specifically, whether they are physical (natural) or spiritual ...
Motsamai Molefe
doaj   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Scale Structure of Moral Adjectives

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.08 In this paper we discuss how and whether moral adjectives fit a well-known semantics for gradable adjectives. We first test whether moral adjectives are relative or absolute adjectives. The preliminary results
Federico L. G. Faroldi   +1 more
doaj  

MORAL STEADFASTNESS AND META-ETHICS [PDF]

open access: yesAmerican Philosophical Quarterly, 2019
Abstract Call the following claim Asymmetry: rationality often requires (or permits) a more steadfast response to pure moral disagreement than it does to otherwise analogous non-moral disagreement. This paper briefly motivates Asymmetry and explores its implications for meta-ethics.
James Fritz, Tristram McPherson
openaire   +1 more source

Others matter. The failure of the autonomous approach to ethics [PDF]

open access: yes, 2017
The critical target of my paper is the normativist stance of Kantian meta ethics. After a very short introduction, I develop a characterization of contemporary mainstream Kantism as a conjunction of a normativist claim, a rationalist claim and a ...
Bertini, Daniele
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Commanding and Obeying

open access: yesPatristica et Mediaevalia, 2012
In this article, it is inquired which reasons are decisive for acting in accordance with divine commands, and whether these can be regarded as moral reasons; the emphasis lies on Christianity.
Jasper Doomen
doaj  

Companions in Guilt Arguments and Moore's Paradox [PDF]

open access: yes, 2017
In a series of articles Christopher Cowie has provided what he calls a ‘Master Argument’ against the Companions in Guilt defence of moral objectivity. In what follows I defend the CG strategy against Cowie.
Campbell, Michael
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

An inquiry into the character of ethical statements and their verification and justification

open access: yesKoers : Bulletin for Christian Scholarship, 1987
Meta-ethics aims at considering questions and problems of fundamental importance to ethics as a science. A central aspect of meta-ethics deals with the character of ethical statements. Are they capable of verification? This is the question examined by
P. J. Hartin
doaj   +1 more source

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