Results 111 to 120 of about 993,269 (287)

Informe Final Práctica Laboral en el Área Arquitectónica, Urbana y Tecnológica

, 2023
Se desarrollan las actividades formativas y prácticas realizadas en la Agencia para la Infraestructura del Meta durante el periodo 2023-2, donde se aplicaron los conocimientos obtenidos en el proceso formativo de la facultad de arquitectura en un ...
Navarro Hernández, Camila
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Informe de prácticas profesionales para optar al grado de Ingeniería Civil: Realizadas en Secretaria de Planeación e Infraestructura de la Alcaldía de Granada-Meta

, 2020
Formular políticas que garanticen el desarrollo procesos de planificación en el municipio, liderando un proceso estratégico hacia el desarrollo integral de toda la jurisdicción municipal y la construcción de una infraestructura que se corresponda con ...
Agudelo Samudio, Jhorman Andres
core  

Informe de práctica laboral para optar el grado de Ingeniería Civil: Elaboración y formulación de proyectos en agencia para la infraestructura del Meta AIM

, 2022
Aportar y aplicar conceptos técnicos y administrativos demostrando la capacidad y entrega que tengo para aprender buscando alternativas y aplicando el desarrollo de conocimientos adquiridos en la Corporación Universitaria Del Meta, durante mi periodo ...
Garcia Medina, Luisa Daniela
core  

Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation

Advanced Science, EarlyView.
ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi, Anna Pasini, Domenico Romanazzi, Margherita Covelli, Vincenzo Romei   +4 more
wiley   +1 more source

Ethical implications of using general-purpose LLMs in clinical settings: a comparative analysis of prompt engineering strategies and their impact on patient safety

BMC Medical Informatics and Decision Making
Background The rapid integration of large language models (LLMs) into healthcare raises critical ethical concerns regarding patient safety, reliability, transparency, and equitable care delivery.
Pouyan Esmaeilzadeh
doaj   +1 more source

Das Verhältnis des Kindes zur Tierwelt : ein Beitrag zur Gemütsbildung

, 1878
von Meta Wellmer ; hrsg.
Wellmer, Meta
core   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source