Results 61 to 70 of about 1,181,348 (259)

The effectiveness of workplace health promotion interventions on physical and mental health outcomes – a systematic review of reviews

open access: yesScandinavian Journal of Work, Environment & Health, 2019
OBJECTIVE: This systematic review aimed to provide an overview of the effectiveness of health promotion interventions at the workplace on physical and mental health outcomes related to chronic diseases.
Karin I Proper, Sandra H van Oostrom
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

A Meta-Review of the Management Development Literature [PDF]

open access: yesHuman Resource Development Review, 2005
An appraisal of recent reviews of the literature on management development demonstrates the existence of a number of perspectives on the topic, and this lack of a uniform approach has contributed to confusion about the subject. This article examines a series of recent and existing literature reviews on the topic of management development.
Cullen, John G., Turnbull, Sharon
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Associations of antidiabetic drugs with diabetic retinopathy in people with type 2 diabetes: an umbrella review and meta-analysis

open access: yesFrontiers in Endocrinology
BackgroundDiabetic retinopathy (DR) is the most frequent complication of type 2 diabetes and remains the leading cause of preventable blindness. Current clinical decisions regarding the administration of antidiabetic drugs do not sufficiently incorporate
Luyuan Tan   +11 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A META-REVIEW OF MANAGEMENT INSIGHTS

open access: yesJournal of Science and Technology - IUH, 2020
There are several overlaps in terms of management. Different books and different scientists approach different subsets of management definitions. This research has been carried out:First, through a series of literature reviews, to capture all aspects of the management term.Second, to shape a systematic relationship enough supporting the term ...
openaire   +2 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

A Meta-Review of the Smartphone as the Measurement Device

open access: yesJournal of Physics: Conference Series, 2020
Abstract With the development of increasingly affordable smartphone technology that is owned by almost everyone, making some activities can be done only by using this device. Smartphone computing capability that is quite powerful, accompanied by various sensors embedded in it, allows the smartphone to be used as a measurement device in ...
B S Hantono   +3 more
openaire   +1 more source

Mapping and systematic appraisal of umbrella reviews in epidemiological research: a protocol for a meta-epidemiological study

open access: yesSystematic Reviews, 2023
Introduction Umbrella review is one of the terms used to describe an overview of systematic reviews. During the last years, a rapid increase in the number of umbrella reviews on epidemiological studies has been observed, but there is no systematic ...
Lazaros Belbasis   +5 more
doaj   +1 more source

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