Results 71 to 80 of about 1,080,671 (301)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Prevention of alcohol and drug misuse in adolescents: An overview of systematic reviews

Nordic Studies on Alcohol and Drugs, 2015
BACKGROUND - Systematic reviews have evaluated a wide variety of programmes aiming to prevent, reduce or delay substance use in adolescents. This paper presents an overview of recent systematic reviews, summarising the evidence on the effectiveness of ...
Emmers Elke, Bekkering Geertruida Elsiena, Hannes Karin   +2 more
doaj   +1 more source

Toothbrushing to address gingivitis [PDF]

, 2015
Background.—The toothbrush is the most widely used homecare method for controlling plaque, with a twice daily regimen commonly considered the best approach.
Akouchekian, Mohadese., Amjadi, Mahak., Nejatidanesh, Farahnaz.   +2 more
core  

Supported self-management for people with type 2 diabetes:a meta-review of quantitative systematic reviews [PDF]

, 2018
OBJECTIVES: Self-management support aims to give people with chronic disease confidence to actively manage their disease, in partnership with their healthcare provider.
,, Captieux, Mireille, Epiphaniou, Eleni, Parke , Hannah L, Pearce , Gemma, Pinnock, Hilary, Taylor, Stephanie J. C., Wild, Sarah   +7 more
core   +2 more sources

Mediterranean diet and health outcomes: a systematic meta-review [PDF]

European Journal of Public Health, 2018
The Mediterranean diet (MeDi) is considered a healthy dietary pattern, and greater adherence to this diet may improve health status. It also may reduce the social and economic costs of diet-related illnesses. This meta-review aims to summarize, synthesize and organize the effects of MeDi pattern on different health outcomes.This meta-review was ...
Roberto Martinez-Lacoba, Isabel Pardo-Garcia, Elisa Amo-Saus, Francisco Escribano-Sotos   +3 more
openaire   +3 more sources

A meta-review of psychological resilience during COVID-19

npj Mental Health Research, 2022
Abstract Psychological resilience has emerged as a key factor in mental health during the global COVID-19 pandemic. However, no work to date has synthesised findings across review work or assessed the reliability of findings based on review work quality, so as to inform public health policy.
Katie Seaborn, Kailyn Henderson, Jacek Gwizdka, Mark Chignell   +3 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Identifying immersive environments’ most relevant research topics: an instrument to query researchers and practitioners [PDF]

, 2018
This paper provides an instrument for ascertaining researchers’ perspectives on the relative relevance of technological challenges facing immersive environments in view of their adoption in learning contexts, along three dimensions: access, content ...
Gaspar, Horácio, Gütl, Christian, Manjón, Baltasar, Morgado, Leonel, São Mamede, Henrique   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Electroplankton revisited: A Meta-Review

Eludamos: Journal for Computer Game Culture, 2007
When it was released, Electroplankton was avant-garde. Today it looks more like a tame specimen of the wave of non-games, music-games and art games that washes over the gaming market. This review reflects on changes of the landscape of gaming ocurring with and after the release of Electroplankton tracing them in the way the game was received by game ...
openaire   +3 more sources