Results 51 to 60 of about 50,414,514 (344)

Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta‐analysis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Sarcopenia is defined as the loss of muscle mass and strength. Despite the seriousness of this disease, a single diagnostic criterion has not yet been established. Few studies have reported the prevalence of sarcopenia globally, and there is a high level
Fanny Petermann-Rocha   +6 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A Meta-analysis of acupoint application in the treatment of dysphagia after stroke (穴位贴敷治疗脑卒中后吞咽障碍的Meta分析)

open access: yes中西医结合护理, 2023
Objective To systematically evaluate the efficacy of acupoint application in the treatment of post-stroke dysphagia. Methods PubMed, Embase, the Cochrane Library, Web of Science, CNKI, VIP, Wanfang databases and CMB were searched for studies on ...
SI Huijie (佀惠婕)   +5 more
doaj   +1 more source

PERANCANGAN DAN PEMBUATAN JIG AND FIXTURE DENGAN MESIN COMPUTER NUMERICAL CONTROL (CNC) MILLING DI PT PRIMA ANUGRAH TEKNIK [PDF]

open access: yes
ABSTRAK Perusahaan industri salah satunya yaitu industri manufaktur, dapat membantu di bidang perkembangan industri. Industri manufaktur menjadi salah satu yang berperan penting di dalam perkenomoian Indonesia .
Prasetiyo, Joko, Widodo, Agus
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

A Meta-analysis of the effect of integrated Traditional Chinese and Western medicine on abdominal distention and constipation after surgery for thoracolumbar fracture (中西医结合治疗胸腰段骨折术后腹胀便秘疗效的Meta分析)

open access: yes中西医结合护理, 2022
Objective To evaluate the clinical effect of integrated Traditional Chinese and Western medicine on abdominal distention and constipation after surgery for thoracolumbar fracture.
SUN Haichao (孙海超)   +3 more
doaj   +1 more source

A parametric meta‐analysis

open access: yesStatistics in Medicine, 2019
In a meta‐analysis, we assemble a sample of independent, nonidentically distributed p‐values. The Fisher's combination procedure provides a chi‐squared test of whether the p‐values were sampled from the null uniform distribution. After rejecting the null uniform hypothesis, we are faced with the problem of how to combine the assembled p‐values.
Chang Yu, Daniel Zelterman
openaire   +4 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A Meta analysis on effect of auricular point sticking and pressing therapy in the treatment of hyperemesis gravidarum (耳穴贴压法治疗妊娠恶阻临床疗效的Meta分析)

open access: yes中西医结合护理, 2022
Objective To evaluate the clinical effect of auricular point sticking and pressing therapy in the treatment of hyperemesis gravidarum. Methods Use of computer to search Cochrane, PubMed, China Knowledge Network Full Text Database (CNKI), VIP Database ...
TIAN Tian (田恬)   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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