Results 51 to 60 of about 4,503,771 (294)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

open access: yesJournal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah   +9 more
doaj   +1 more source

Biologics and oral systemic treatment preferences in patients and physicians for moderate-to-severe atopic dermatitis: a discrete choice experiment in the United Kingdom and Germany

open access: yesJournal of Dermatological Treatment
Background: As the available treatments for moderate-to-severe atopic dermatitis (AD) expand, understanding patient and physician preferences becomes crucial for informed decision-making.Objective: To quantify patient and physician preferences for ...
Nicholas Durno   +12 more
doaj   +1 more source

The role of IL-6 for predicting neonatal sepsis: A systematic review and meta-analysis [PDF]

open access: yes, 2011
Objective: Neonatal sepsis (NS) is a common and life-threatening disorder in infants. Previous studies showed that interleukin-6 (IL-6) may be a valid non-invasive and rapid method for diagnosis of NS.
Ahani, A.   +4 more
core   +1 more source

Meta-analysis in Otolaryngology [PDF]

open access: yesArchives of Otolaryngology–Head & Neck Surgery, 2000
To examine the results of meta-analyses in otolaryngology and compare these results with the individual component studies that constitute each meta-analysis.A retrospective review of the literature.Studies that conducted pooled statistical systematic analyses indexed on MEDLINE for the 10-year period from January 1989 to January 1999 were selected for ...
R, Alsarraf   +3 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

American trade policy towards Sub Saharan Africa –- a meta analysis of AGOA [PDF]

open access: yes, 2011
Twelve econometric studies investigating the impact of agoa presented in this paper have reported 174 different estimates. In testing for publication bias and whether there is a genuine empirical impact of agoa we resort to a meta-analysis.
Cooke, Edgar F A
core  

ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis. [PDF]

open access: yes, 2016
Meta-analysis has become a popular tool for genetic association studies to combine different genetic studies. A key challenge in meta-analysis is heterogeneity, or the differences in effect sizes between studies.
Eskin, Eleazar   +5 more
core   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

META ANALYSIS OF THE EFFECT OF CLASSROOM MANAGEMENT ON STUDENT LEARNING OUTCOMES IN ELEMENTARY SCHOOLS

open access: yesPrimary: Jurnal Pendidikan Guru Sekolah Dasar, 2020
Classroom management is very important in the teaching and learning process with proper and appropriate classroom management, students will feel comfortable and happy when receiving learning materials so that learning outcomes are expected to be better ...
Zahrotun Nafisah   +3 more
doaj   +1 more source

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