Results 61 to 70 of about 50,414,514 (344)

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

Journal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah, Helia Mojtabavi, Atefeh Behkar, Arash Heidari, Atra Ajdari, Zoha Shaka, Seyed Vahid Mousavi, Negar Firoozeh, Abbas Tafakhori, Nima Rezaei   +9 more
doaj   +1 more source

Biologics and oral systemic treatment preferences in patients and physicians for moderate-to-severe atopic dermatitis: a discrete choice experiment in the United Kingdom and Germany

Journal of Dermatological Treatment
Background: As the available treatments for moderate-to-severe atopic dermatitis (AD) expand, understanding patient and physician preferences becomes crucial for informed decision-making.Objective: To quantify patient and physician preferences for ...
Nicholas Durno, Pablo Arija, Krystallia Pantiri, Marieke Heisen, Marco Boeri, Josef Paris, Katrin Jack, Olivier Chambenoit, Ramkumar Subramanian, Jorge Puelles, Elly Stolk, Ben van Hout, Jonathan I. Silverberg   +12 more
doaj   +1 more source

Practical methods for incorporating summary time-to-event data into meta-analysis

Trials, 2007
BackgroundIn systematic reviews and meta-analyses, time-to-event outcomes are most appropriately analysed using hazard ratios (HRs). In the absence of individual patient data (IPD), methods are available to obtain HRs and/or associated statistics by ...
J. Tierney, L. Stewart, D. Ghersi, S. Burdett, M. Sydes   +4 more
semanticscholar   +1 more source

rgs212/Meta-analysis-Smith: Methylation Meta analysis Smith et al

, 2021
Release of "A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex" by Smith and Pishva et al ...
Gemma Shireby, Gilles Gasparoni, Ehsan Pishva, Rebecca G. Smith, Gregory Wheildon, Vahram Haroutunian, Daniel L.A. van den Hove, Andrew J. Sharp, Janou A.Y. Roubroeks, Armin Giese, Wolfgang Viechtbauer, Katie Lunnon, Adam R. Smith, Paul D. Coleman, Eilis Hannon, Diego Mastroeni, Jonathan Mill, Michael Weedon, Jörn Walter, David A. Bennett, Leonard Schalkwyk, Matthias Riemenschneider, Philip L. De Jager   +22 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

METAL: fast and efficient meta-analysis of genomewide association scans

Bioinform., 2010
Summary: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies.
C. Willer, Yun Li, G. Abecasis
semanticscholar   +1 more source

Informe de práctica empresarial, Alcaldía de Restrepo

, 2023
Informe de práctica profesional del programa de Comunicación Social y PeriodismoLa Alcaldía de Restrepo se crea cuando por medio del Decreto 904 del 23 de septiembre de 1912 cuando el caserío La Concepción fue elevado a la categoría de municipio ...
Sandoval Cisneros, Laura Camila
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

META ANALYSIS OF THE EFFECT OF CLASSROOM MANAGEMENT ON STUDENT LEARNING OUTCOMES IN ELEMENTARY SCHOOLS

Primary: Jurnal Pendidikan Guru Sekolah Dasar, 2020
Classroom management is very important in the teaching and learning process with proper and appropriate classroom management, students will feel comfortable and happy when receiving learning materials so that learning outcomes are expected to be better ...
Zahrotun Nafisah, Nafiah, Muhammad Thamrin Hidayat, Sri Hartatik   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source