Results 91 to 100 of about 3,290,125 (315)
Editorial: Methods and applications in metabolic physiology
Frontiers in Physiology, 2023 Amy C. Arnold, Kamal Rahmouni
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products [PDF]
, 2012 Zahoor ul Hassan A, Lindner S, Wendisch VF. Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products. Computational and Structural Biotechnology Journal.
Volker F. Wendisch +5 more
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Topological peculiarities of mammalian networks with different functionalities: transcription, signal transduction and metabolic networks [PDF]
Network Biology, 2011 We have comparatively investigated three different mammalian networks - on transcription, signal transduction and metabolic processes - with respect to their common and individual topological traits.
Bjorn Goemann +2 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Editorial: Insights in integrative physiology: 2021
Frontiers in Physiology, 2023 James T. Pearson +3 more
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Rare presentation of Kyrle′s disease in siblings
Indian Journal of Dermatology, 2008 Background: Kyrle′s disease is a rare variant of primary perforating dermatosis. Its occurrence in a familial setting, especially in children, is extremely uncommon.
Viswanathan Seethalakshmi +4 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
JAMA: The Journal of the American Medical Association, 1909 In my student days in Germany during the winter semester of 1898, I visited the laboratory of the botanical garden of Munich to call on Oscar Loew, who had some time before been assistant to Dr. R. Ogden Doremus in the City College of New York. Loew showed me how he was passing the vapor of methyl-alcohol (CH3CH) over hot oxidized wire gauze and ...
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