Results 41 to 50 of about 1,404,860 (382)

Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. [PDF]

PLoS Genetics, 2010
Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast cancer
Julia Ling-Yu Chen, Daniel Merl, Christopher W Peterson, Jianli Wu, Patrick Yantyng Liu, Hanwei Yin, Deborah M Muoio, Don E Ayer, Mike West, Jen-Tsan Chi   +9 more
doaj   +1 more source

Effect of sodium bicarbonate infusion on hospital mortality in acute kidney injury patients with metabolic acidosis

Frontiers in Medicine, 2023
BackgroundPhysicians usually consider that sodium bicarbonate (SB) infusion can be used for metabolic acidosis; however, there is little evidence available to assess its effect on hospital mortality in large AKI cohorts.
Yunting Wang, Yunting Wang, Ling Chen, Guangfeng Guo, Youyuan Gao, Youyuan Gao, Hua Gan   +6 more
doaj   +1 more source

Chronic Kidney Disease in Cats and the Risk of Total Hypercalcemia [PDF]

, 2017
BACKGROUND: Chronic kidney disease (CKD) is a common comorbidity in cats with hypercalcemia, but whether CKD is a risk factor for hypercalcemia is unclear.
Abdi, Andress, Barber, Barber, Barber, Berend, Berry, Bertazzolo, Bienzle, Blaine, Block, Burnell, Bushinsky, Chakrabarti, Cole, Costanzo, DiBartola, Elliott, Elliott, Eren, Finch, Flanders, Fogh-Andersen, Gal, Gauci, Geddes, Geddes, He, Jackson, Kelly, Kogika, Kovesdy, Kurz, Lemann, Levi, Levi, Lulich, Malatesha, Marino, Marone, McLeland, Meghji, Meuten, Midkiff, Must, Payne, Peacock, Picolos, Pieper, Piraino, Polzin, Rafferty, Savary, Schenck, Schenck, Schenck, Schenck, Schenck, Schenck, Schenck, Shanahan, Shipov, Sutton, Tentori, Williams, Yamada, Yang   +66 more
core   +2 more sources

Early pH Changes in Musculoskeletal Tissues upon Injury-Aerobic Catabolic Pathway Activity Linked to Inter-Individual Differences in Local pH [PDF]

, 2020
Local pH is stated to acidify after bone fracture. However, the time course and degree of acidification remain unknown. Whether the acidification pattern within a fracture hematoma is applicable to adjacent muscle hematoma or is exclusive to this ...
Berkmann, Julia C., Duda, Georg N., Ellinghaus, Agnes, Lippens, Evi, Martin, Aaron X. Herrera, Schell, Hanna, Schlundt, Claudia, Schmidt-Bleek, Katharina, Tsitsilonis, Serafeim   +8 more
core   +2 more sources

Prevalence and severity of metabolic acidosis in patients on maintenance hemodialysis in India

Medical Journal of Dr. D.Y. Patil University, 2016
Aim: Metabolic acidosis is a feature of chronic kidney disease (CKD) due to the reduced capacity of the kidney to synthesize ammonia and excrete hydrogen ions.
Atul D Sajgure, Tushar A Dighe, Jayraj S Korpe, Charan B Bale, Ashwini O Sharma, Nilesh S Shinde, Abhishek A Goel, Atul V Mulay   +7 more
doaj   +1 more source

Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study

JN. Journal of Nephrology (Milano. 1992), 2019
Metabolic acidosis is associated with accelerated progression of chronic kidney disease (CKD). Whether treatment of metabolic acidosis with sodium bicarbonate improves kidney and patient survival in CKD is unclear.
B. D. Di Iorio, A. Bellasi, K. Raphael, D. Santoro, F. Aucella, L. Garofano, M. Ceccarelli, L. Di Lullo, G. Capolongo, Mattia Di Iorio, P. Guastaferro, G. Capasso, Vincenzo Annamaria Valeria Giuseppe Vincenzo Adamasco Anton Barbera Bruzzese Canale Conte Crozza Cupisti De Bl, V. Barbera, A. Bruzzese, V. Canale, G. Conte, Vincenzo Crozza, A. Cupisti, A. De Blasio, E. De Simone, L. Di Micco, F. Fiorini, R. Grifa, R. Nardone, M. Piemontese, M. Sirico, F. Vitale   +27 more
semanticscholar   +1 more source

Seizure Disorders in Goats and Sheep. [PDF]

, 2016
BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
core   +1 more source

Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism. [PDF]

, 2020
Recent studies have identified both recessive and dominant forms of mitochondrial disease that result from ATAD3A variants. The recessive form includes subjects with biallelic deletions mediated by non-allelic homologous recombination.
Armstrong, C, Baple, E, Baptista, J, Caswell, R, Cunningham, MH, Dean, J, Durigon, R, Durlacher-Betzer, K, Ellard, S, Fernandez Pelayo, U, Grochowski, CM, Gunning, AC, Harel, T, Holt, IJ, Homfray, T, Jones, AWE, Lahiri, N, Lupski, JR, Misra, VK, Muñoz Oreja, M, Parrish, A, Scurr, I, Spinazzola, A, Stals, KL, Strucinska, K, Taylor, RW, Tysoe, C, Wright, CF, Yoon, WH   +28 more
core   +3 more sources

Metabolic Acidosis in CKD: Core Curriculum 2019.

American Journal of Kidney Diseases, 2019
Maintenance of normal acid-base homeostasis is one of the most important kidney functions. In chronic kidney disease, the capacity of the kidneys to excrete the daily acid load as ammonium and titratable acid is impaired, resulting in acid retention and ...
K. Raphael
semanticscholar   +1 more source

Metabolic Acidosis

Critical Care, 2021
S. Mensack
openaire   +2 more sources