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Metabolism and metabolic burden by α1-antitrypsin production in human AGE1.HN cells

Metabolic Engineering, 2013
The metabolic burden on human AGE1.HN cells imposed by the production of recombinant α1-antitrypsin (A1AT) was studied by comparing a selected high-producing clonal cell line with the parental cell line. RNA, lipid, and phosphatidylcholine fractions were higher in the producer cell line causing metabolic changes in the producer, e.g., increased glycine
Jens, Niklas   +4 more
openaire   +2 more sources

Myocardial deformation and twist mechanics in adults with metabolic syndrome: Impact of cumulative metabolic burden

Obesity, 2013
ObjectiveThe aim of the study is to characterize left ventricular (LV) myocardial mechanics in adults with metabolic syndrome (MetS), and elucidate the effects of multiple risk‐factors on myocardial function using speckle tracking echocardiography (STE); a more sensitive method than conventional echocardiography for detecting subclinical myocardial ...
Crendal, Edward   +9 more
openaire   +4 more sources

The global burden of metabolic disease: Data from 2000 to 2019

Cell Metabolism, 2023
Yock Young Dan   +2 more
exaly  

Mechanical Surgery Eases the Burden of Metabolic Disease

Journal of the American College of Surgeons, 2020
openaire   +2 more sources

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