Results 51 to 60 of about 172,525 (164)

Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies.

PLoS ONE, 2020
There continues to be a significant shortage of donor livers for transplantation. One impediment is the discard rate of fatty, or steatotic, livers because of their poor post-transplant function.
Siavash Raigani, Negin Karimian, Viola Huang, Anna M Zhang, Irene Beijert, Sharon Geerts, Sonal Nagpal, Ehab O A Hafiz, Fermin M Fontan, Mohamed M Aburawi, Paria Mahboub, James F Markmann, Robert J Porte, Korkut Uygun, Martin Yarmush, Heidi Yeh   +15 more
doaj   +1 more source

Interplay between key metabolic hormones, metabolic factors, renal function, and heart rate variability in humans with obesity

Scientific Reports
This study aimed to provide the first integrative assessment of clinical, metabolic, renal, hormonal, and heart rate variability (HRV) parameters in individuals with obesity, stratified by metabolic syndrome (MetS) and insulin resistance (IR), clarifying
Kitchaya Pongwattanapakin, Chit Care, Chantacha Sitticharoon, Kittikorn Tommy Wilasrusmee, Issarawan Keadkraichaiwat, Pailin Maikaew, Rungnapa Sririwichitchai   +6 more
doaj   +1 more source

Size and dose of nanoparticles modulate between toxic and medicinal effect on kidney

OpenNano
To know when a nanoparticle (NP) is toxic and when a NP is medicinal, we need to elucidate the various biochemical interactions exerted by NPs within the body. Clearance is an important pharmacological parameter and property.
Tom M. Nolte, Bingqing Lu
doaj   +1 more source

Glucose driven bacterial persistence in extensively drug-resistant tuberculosis with diabetes

Frontiers in Public Health
BackgroundDiabetes mellitus (DM) disrupts the metabolic environment of extensively drug-resistant tuberculosis (XDR) patients, promoting mycobacterial persistence. Key factors influencing bacterial clearance remain unclear.
Xin Yao, Xin Yao, Yarong Shi, Yarong Shi, Minghao Kong, Minghao Kong, Yujie Zhang, Yujie Zhang, Jianxia Chen, Wenjuan Wang, Zhonghua Liu, Zhonghua Liu   +11 more
doaj   +1 more source

Understanding glucose transporter type 4, aka GLUT4: a novel review

Revista Mexicana de Endocrinología, Metabolismo y Nutrición
Glucose transporter (GLUT4), discovered in 1988, is primarily located in adipocytes and muscle cells. Its unique transport mechanism is characterized by a 10-fold increase in exocytosis rate, which is dependent on insulin.
Karen De La Vega-Moreno, Juan A. Suárez-Cuenca   +1 more
doaj   +1 more source

Concepts of Lactate Metabolic Clearance Rate and Lactate Clamp for Metabolic Inquiry: A Mini-Review. [PDF]

Nutrients, 2023
Emhoff CW, Messonnier LA.
europepmc   +1 more source

Analysis of particle size and lipid composition as determinants of the metabolic clearance of human high density lipoproteins in a rabbit model

Journal of Lipid Research, 1998
Hypertriglyceridemia is commonly associated with triglyceride (TG) enrichment of high density lipoprotein (HDL) and reduction in HDL cholesterol and apolipoprotein A-I levels.
Benoît Lamarche, Kristine D. Uffelman, George Steiner, P. Hugh R. Barrett, Gary F. Lewis   +4 more
doaj   +1 more source

Prognostic Value of Arterial Lactate Metabolic Clearance Rate in Moderate and Severe Acute Pancreatitis. [PDF]

Dis Markers, 2022
Zeng J, Wan J, He W, Zhu Y, Zeng H, Liu P, Gong M, Liu F, Shao Q, Xia L, Zhu Y, Chen Y, Lu N.   +12 more
europepmc   +1 more source

Metabolism of apoB lipoproteins of intestinal and hepatic origin during constant feeding of small amounts of fat

Journal of Lipid Research, 2006
We aimed to identify mechanisms by which apolipoprotein B-48 (apoB-48) could have an atherogenic role by simultaneously studying the metabolism of postprandial apoB-48 and apoB-100 lipoproteins.
Chunyu Zheng, Katsunori Ikewaki, Brian W. Walsh, Frank M. Sacks   +3 more
doaj   +1 more source

Postprandial changes of apoB-100 and apoB-48 in TG rich lipoproteins in familial combined hyperlipidemia

Journal of Lipid Research, 2002
Impaired chylomicron (chylo) remnant clearance and small VLDL overproduction are major metabolic abnormalities in familial combined hyperlipidemia (FCHL). Quantitative data on postprandial apolipoprotein B-48 (apoB-48) and apolipoprotein B-100 (apoB-100)
C. Verseyden, S. Meijssen, M. Castro Cabezas   +2 more
doaj   +1 more source