Results 221 to 230 of about 1,774 (249)
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CCN family member 1 deregulates cholesterol metabolism and aggravates atherosclerosis
Acta Physiologica, 2018AbstractAimCCN family member 1 (CCN1) is an extracellular matrix cytokine and appears in atherosclerotic lesions. However, we have no evidence to support the role of CCN1 in regulating cholesterol metabolism and atherosclerosis.MethodsApolipoprotein E‐deficient (apoE−/−) mice were used as in vivo model.
Jin‐Feng Zhao +4 more
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Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice
Blood, 2005Abstract Evidence is accumulating that hepcidin, a liver regulatory peptide, could be the common pathogenetic denominator of all forms of iron overload syndromes including HFE-related hemochromatosis, the most prevalent genetic disorder characterized by inappropriate iron absorption. To understand the mechanisms whereby hepcidin controls
Lydie, Viatte +7 more
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Antitumor and chemosensitizing action of 3-bromopyruvate: Implication of deregulated metabolism
Chemico-Biological Interactions, 20173-Bromopyruvate (3-BP), brominated derivative of pyruvate, possesses strong antitumor potential, owing to its ability to inhibit multiple target molecules crucial for survival of neoplastic cells. Although, 3-BP displays cytotoxicity against a wide variety of tumors, there is no report with respect to malignancies of thymic origin.
Saveg, Yadav +5 more
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Metabolic Deregulations in Acute Myeloid Leukemia
2021Mondet J, Chevalier S, Mossuz P
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Physiological limitations and opportunities in microbial metabolic engineering
Nature Reviews Microbiology, 2021José Montaño López, Jose L Avalos
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[Deregulation of homocysteine metabolism and consequences for the vascular system].
Bulletin de l'Academie nationale de medecine, 1997The link between vascular disease and elevated homocysteine levels has been recognized for more than 30 years, and association with moderately elevated levels has been suspected for 20 years. Homocysteine is a sulfhydryl-containing amino acid that is formed by the demethylation of methionine.
J P, Nicolas, A, Chango
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Therapeutic RNA-silencing oligonucleotides in metabolic diseases
Nature Reviews Drug Discovery, 2022Markus Stoffel
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Gut microbiota in human metabolic health and disease
Nature Reviews Microbiology, 2020Yong Fan, Oluf Borbye Pedersen
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Metabolic Engineering: Methodologies and Applications
Chemical Reviews, 2023Pu Xue, Huimin Zhao
exaly
Metabolic regulation of gene expression through histone acylations
Nature Reviews Molecular Cell Biology, 2016Benjamin R Sabari +2 more
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