Results 251 to 260 of about 1,855,857 (359)

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Significant Association Between Glucokinase Regulatory Protein Variants and Genetic and Metabolic Diseases. [PDF]

Curr Issues Mol Biol
Xu K, Chen P, Su Y, Chen Y, Song X, Yu B, Wang H.   +6 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The Rising Global Burden of MASLD and Other Metabolic Diseases (2000-2021). [PDF]

United European Gastroenterol J
Danpanichkul P, Suparan K, Diaz LA, Fallon MB, Chen VL, Namsathimaphorn K, Rakwong K, Inkongngam T, Kaeosri C, Kalligeros M, Wattanachayakul P, Ng CH, Takahashi H, Huang DQ, Muthiah MD, Arab JP, Kim D, White TM, Noureddin M, Bugianesi E, Jepsen P, Wong VWS, Lazarus JV, Wijarnpreecha K.   +23 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Trends in AI-based diagnosis and intervention of metabolic diseases: a bibliometric analysis of the literature from 2000 to 2024. [PDF]

Front Med (Lausanne)
Chen B, Wang Y, Xie X, Fan B, Zhang W, Sun G.   +5 more
europepmc   +1 more source

Functional PET for mapping metabolic dynamics in Parkinson’s disease [PDF]

Vanessa Heinecke, Lilly Machholz, Kenan Steidel, Lenna M. Rüsing, Falk K. Thiemig, Damiano Librizzi, Maya Beckersjürgen, Jennifer Fuchs, Markus Luster, Lars Timmermann, David J. Pedrosa, Marina C. Ruppert   +11 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Delivering the Message: Translating mRNA Therapy for Liver Inherited Metabolic Diseases. [PDF]

J Inherit Metab Dis
Gurung S, Perocheau D, Ghosh R, Hart SL, Baruteau J.   +4 more
europepmc   +1 more source

A case of connective tissue disease complicated by multiple metabolic disorders

, 2010
Milan K. Piya, Abd A. Tahrani, Philip Dyer, Jayadave Shakher, Alan Jones, Manchester   +5 more
openalex   +1 more source