Results 251 to 260 of about 996,145 (295)

The Interplay Between Adipokines and Body Composition in Obesity and Metabolic Diseases. [PDF]

Cureus
Zadgaonkar U.
europepmc   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Adaptation of the nutrition care process for metabolic diseases in the Mexican population. [PDF]

Front Nutr
Sevilla-González M, González-Ortiz A, Landa-Anell MV, Melgarejo-Hernández MA, Arias-Marroquín AT, Del Razo-Olvera FM, Román-Calleja BM, Monreal-Lugo AV, Martin-Vences AJ, Haua-Navarro K, Espinosa-Cuevas A.   +10 more
europepmc   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Exploring CTRP6: a biomarker and therapeutic target in metabolic diseases. [PDF]

Am J Physiol Endocrinol Metab
Senthil Kumar J, Mehboob MZ, Lei X.
europepmc   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

The Role of Reductive Stress in the Pathogenesis of Endocrine-Related Metabolic Diseases and Cancer. [PDF]

Int J Mol Sci
Mladenov M, Sazdova I, Hadzi-Petrushev N, Konakchieva R, Gagov H.   +4 more
europepmc   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Regulation of bile acids and their receptor FXR in metabolic diseases. [PDF]

Front Nutr
Li Y, Wang L, Yi Q, Luo L, Xiong Y.
europepmc   +1 more source

Revisiting the role of IL-27 in obesity-related metabolic diseases: safeguard or perturbation? [PDF]

Front Immunol
An J, Fu D, Chen X, Guan C, Li L, Bai J, Lv H.   +6 more
europepmc   +1 more source